THE INTERRELATIONSHIP OF WEIGHT-LOSS, DIETARY-INTAKE, AND QUALITY-OF-LIFE IN AMBULATORY PATIENTS WITH CANCER OF THE LUNG, BREAST, AND OVARY
THE INTERRELATIONSHIP OF WEIGHT-LOSS, DIETARY-INTAKE, AND QUALITY-OF-LIFE IN AMBULATORY PATIENTS WITH CANCER OF THE LUNG, BREAST, AND OVARY
复制标题
DOI：
10.1080/01635589309514246
复制
发表时间：
1993-01-01
影响因子：
2.9
通讯作者：
MORTENSEN, EL
中科院分区：
文献类型：
--
作者：
OVESEN, L;HANNIBAL, J;MORTENSEN, EL
连续 104 名新诊断的小细胞肺癌、转移性乳腺癌和卵巢癌患者，身体功能状况良好（东部肿瘤合作组量表评分 0-1），分为减肥组（3 个月内无意识体重减轻大于或等于 5%；n = 48）和体重稳定组（n = 56）。两组中与去脂体重相关的膳食摄入量没有差异。根据生活质量指数和一般健康问卷，体重减轻患者的生活质量明显低于体重稳定患者。在体重减轻的患者中，每日能量和蛋白质摄入量与一般健康问卷得分显着相关。这项研究表明，许多卧床癌症患者的饮食不足以维持体重，即使是适度的体重减轻也会导致心理困扰和生活质量下降。
One hundred four consecutive patients with newly diagnosed small cell lung cancer, metastatic breast cancer, and ovarian cancer in good physical functional condition (performance rating 0-1 on Eastern Cooperative Oncology Group scale) were divided into a weight-losing group (greater-than-or-equal-to 5% unintentional weight loss within 3 mo; n = 48) and a weight-stable group (n = 56). Dietary intakes in relation to fat-free mass were not different in the two groups. According to the Quality of Life index and the General Health Questionnaire, weight-losing patients had significantly lower quality of life than weight-stable patients. In patients with weight loss, daily intakes of energy and protein correlated significantly with scores on the General Health Questionnaire. This study has shown that many ambulatory cancer patients do not eat enough to maintain weight and that even a moderate weight loss is associated with psychological distress and lower quality of life.