Changes in neuropsychological performance during treatment for alcoholism.

Changes in neuropsychological performance during treatment for alcoholism.
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酒精中毒治疗期间神经心理学表现的变化。

DOI:
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发表时间:
1979
影响因子:
10.6
通讯作者:
L. Gottschalk
L. Gottschalk
中科院分区:
医学1区
文献类型:
--
作者:
M. Eckardt;E. S. Parker;E. Noble;C. Pautler;L. Gottschalk

文献摘要

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一组24项神经心理学测试在他们最后一次饮酒的7天内和17天后对无药物的酗酒住院患者(n = 91)进行。这一组和非酒精组的医疗住院患者(n = 20)之间的比较,也给予相同的测试电池两次表明很少改善,由于戒酒(短期改善)后,控制实践效果的酗酒者。同样,当酒精成瘾者的早期戒断后表现与酒精对照组(n = 32)进行比较时,酒精对照组在他们最后一次饮酒后21天只进行了一次测试,几乎没有证据表明认知功能短期恢复。由于依赖于认知过程的治疗性治疗的开始决定是基于神经心理学的表现,我们得出结论,这种治疗可能会开始尽快与急性戒断相关的临床症状已经消退。
A battery of 24 neuropsychological tests was administered to drug-free alcoholic inpatients (n = 91) within 7 days of their last drink and again 17 days later. Comparisons between this group and a nonalcoholic group of medical inpatients (n = 20) also given the same test battery twice indicated very little improvement due to abstinence (short-term improvement) in the alcoholics after controlling for practice effects. Similarly, when early postwithdrawal performance of the alcoholics was compared to an alcoholic control group (n = 32), which took the test battery only once 21 days after their last drink, little evidence for short-term recovery of cognitive functions was obtained. Insofar as decisions about the initiation of therapeutic treatments which rely on cognitive processes are based on neuropsychological performance, we conclude that such treatments may commence as soon as the clinical symptoms associated with acute withdrawal have subsided.