Differential temporo-parietal cortical networks that support relational and item-based recency judgments
Differential temporo-parietal cortical networks that support relational and item-based recency judgments
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DOI：
10.1016/j.neuroimage.2009.11.003
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发表时间：
2010-02-15
期刊：
影响因子：
5.7
通讯作者：
Konishi, Seiki
中科院分区：
文献类型：
--
作者：
Kimura, Hiroko M.;Hirose, Satoshi;Konishi, Seiki
顶叶皮层在情景记忆提取中的作用越来越受到人们的关注。以往的功能性磁共振成像（fMRI）研究近因判断，两个研究项目的相对时间顺序的判断，突出了外侧前额叶和内侧颞区的参与。然而，顶叶皮层的贡献近因判断很少被强调。为了研究顶叶参与，在这项研究中，我们进行了重新分析，以增加统计能力，使用三个数据集（N = 73），从我们以前的功能磁共振成像研究的近因判断。近因判断至少可以通过两种机制来实现，关系机制和基于项目的机制。结果表明，左侧海马/海马旁区与关系近因判断相关，右侧前颞区与基于项目的近因判断相关。我们研究了顶叶皮层是否参与了这两种近因判断。与关系近因判断相关的显著脑活动在左腹顶叶区观察到，如前所述，左海马旁区。在另一方面，显着的大脑活动相关的项目为基础的近因判断观察到在左背顶叶区域，如前所述，右前颞区。此外，相关性分析的休息状态BOLD信号检测腹顶叶区和海马旁区之间的显着相关性，以及背顶叶区和前颞区之间。这些结果表明，这两个颞顶网络的差异有助于关系和项目为基础的近因判断。(C)2009 Elsevier Inc. All rights reserved.
There is a growing interest in the parietal cortical role for episodic memory retrieval. Previous functional magnetic resonance imaging (fMRI) studies of recency judgments, judgments of the relative temporal order of two studied items, have highlighted the involvement of the lateral prefrontal and medial temporal regions. However, the parietal cortical contribution to recency judgments has rarely been highlighted. To examine the parietal involvement, in this study, we conducted a re-analysis to increase the statistical power using three data sets (N = 73) from our previous fMRI studies of recency judgments. Recency judgments can be achieved by at least two mechanisms, relational and item-based ones. It has been revealed that the left hippocampus/parahippocampal region is related to relational recency judgments, and that the right anterior temporal region is related to item-based recency judgments. We examined whether the parietal cortex is involved in these two types of recency judgments. Significant brain activity related to relational recency judgments was observed in the left ventral parietal region and, as reported previously, the left parahippocampal region. On the other hand, significant brain activity related to item-based recency judgments was observed in the left dorsal parietal region and, as reported previously, the right anterior temporal region. Furthermore, correlation analyses of resting-state BOLD signals detected significant correlations between the ventral parietal region and the parahippocampal region, as well as between the dorsal parietal region and anterior temporal region. These results suggest that the two temporo-parietal networks differentially contribute to relational and item-based recency judgments. (C) 2009 Elsevier Inc. All rights reserved.