Impact of the COVID-19 pandemic on recruitment to clinical research studies in rheumatology.
Impact of the COVID-19 pandemic on recruitment to clinical research studies in rheumatology.
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DOI：
10.1002/msc.1561
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发表时间：
2022-03
影响因子：
1.3
通讯作者：
Falahee M
中科院分区：
文献类型：
--
作者：
Mirza M;Siebert S;Pratt A;Insch E;McIntosh F;Paton J;Wright C;Buckley CD;Isaacs J;McInnes IB;Raza K;Falahee M
2.方法于2020年9月11日至2020年11月6日进行匿名在线调查。调查问题由研究人员（包括临床研究人员）和RACE附属患者研究合作伙伴共同制定并达成一致。使用的调查平台是Jisc Online Surveys®。该调查的链接通过NRAS成员通讯和社交媒体平台发布。如果参与者年龄在18岁或以上，并报告他们确诊为RA，则将其纳入研究。该研究包括两个小插曲，每个小插曲描述了一项临床流变学研究-一项观察性研究和一项试验性医疗产品的试验-参与者被要求说明他们参加研究的可能性（a）在COVID-19大流行之前和（B）在COVID-19大流行期间。使用Wilcoxon符号秩检验检验了大流行之前和期间分布评分的差异。参与者还被要求指出研究小组确定的几个因素有可能减轻大流行的限制作用，这些因素对他们参与研究的决策产生积极或消极影响的程度。最后，他们有机会提供开放文本的回应，这些回应由MM和MF独立地分类。通过MM、MF和KR之间的讨论解决主题之间的任何差异。结果
2. METHODAn anonymous online survey was conducted between 11 September 2020 and 6 November 2020. The survey questions were developed and agreed upon by consensus between researchers (including clinical researchers) and patient research partners affiliated with RACE. The survey platform used was Jisc Online Surveys®. A link to the survey was advertised via NRAS newsletters for members and social media platforms. Participants were included if they were aged 18 or older, and reported that they had a confirmed diagnosis of RA. The study included two vignettes, each describing a clinical rheumatological research study—an observational study and a trial of an investigational medical product—where participants were asked to indicate how likely they would be to take part in the study (a) before the COVID‐19 pandemic and (b) during COVID‐19 pandemic. Differences in the distribution scores before and during the pandemic were tested using the Wilcoxon signed‐ranks test. Participants were also asked to indicate the extent to which several factors, identified by the research team as having the potential to mitigate the pandemic's constraining effects, would have a positive or negative impact on their decision‐making about research participation. Finally, they were given the opportunity to provide open‐text responses, which were grouped into categories independently by MM and MF. Any discrepancies between themes were resolved via discussion between MM, MF and KR.3. RESULTS
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影响因子：
2.5
作者：
Mitchell, Eleanor J.;Ahmed, Khaled;McDonald, Alison
通讯作者：
McDonald, Alison
影响因子：
7.4
作者：
Darmawan I;Bakker C;Brockman TA;Patten CA;Eder M
通讯作者：
Eder M
影响因子：
27.4
作者：
Dejaco, Christian;Alunno, Alessia;Buttgereit, Frank
通讯作者：
Buttgereit, Frank
影响因子：
2.9
作者：
Collier, Erin K.;Hsiao, Jennifer L.;Shi, Vivian Y.
通讯作者：
Shi, Vivian Y.
影响因子：
2.7
作者：
Carlisle, Benjamin;Kimmelman, Jonathan;MacKinnon, Nathalie
通讯作者：
MacKinnon, Nathalie