Association Between the Onset of Physical Frailty and Executive Function in Community-Dwelling Elderly People
Association Between the Onset of Physical Frailty and Executive Function in Community-Dwelling Elderly People
复制标题
社区老年人身体虚弱的发生与执行功能之间的关联
DOI：
10.1044/2021_persp-21-00207
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Tanemura Jun
中科院分区：
文献类型：
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作者：
Toda Atsushi;Yano Jitsuro;Tanemura Jun
目的身体虚弱可能会增加患痴呆症的风险，但目前还不清楚认知能力是如何下降的。方法选择2018-07/2020-01在社区日间托儿所就诊的老年人46例，年龄75岁以上，平均年龄(83.2±5.1)岁。受试者被分为身体脆弱组和非脆弱组，并对身体表现和认知功能进行评估。通过计时起跑(TUG)测试、握力、两侧小腿周长和单腿站立时间来测量体能。采用简易智力状态检查量表、瑞文有色累进测验和连线测验(TMT)对受试者进行认知功能评定。体弱组10例，平均年龄82.9±4.0岁；非体弱组18例，平均年龄83.4±3.9岁。体力脆弱组与非体弱组相比，TUG和TMT显著降低。体力衰弱组的TUG与TMT的B部分呈显著正相关(r=0.735，P<0.05)。结论体力衰弱组的执行功能较差，提示可能影响运动能力。根据这些结果，身体虚弱的评估可以通过将体能评估与包括执行功能评估在内的认知功能测试相结合来导致更具战略性的预防和治疗。
PurposePhysical frailty may increase the risk of dementia, but it is not known exactly how cognition decreases. In this study, the features of recognition dysfunction in physical frailty were assessed.MethodThe subjects were 46 elderly people aged 75 years or older (Mage= 83.2 ± 5.1 years) who visited community day care facilities between July 2018 and January 2020. The subjects were divided into a physical frailty group and a nonfrailty group, and physical performance and cognitive function were evaluated. Physical performance was measured by the Timed Up and Go (TUG) test, handgrip strength, lower leg circumference on both sides, and one-leg standing time. The Mini-Mental State Examination, Raven's Colored Progressive Matrices, and the Trail Making Test (TMT) were used to assess cognitive function.ResultsThe subjects were diagnosed based on the Cardiovascular Health Study criteria, in particular, Cardiovascular Health Study diagnostic items based on the Japanese version criteria. The physical frailty group included 10 subjects with an average age of 82.9 ± 4.0 years, and the nonfrailty group included 18 subjects with an average age of 83.4 ± 3.9 years. The physical frailty group showed significantly lower TUG and TMT compared with the nonfrailty group. There was also a significant correlation between TUG and Part B of the TMT in the physical frailty group (r = 0.735,p< .05).ConclusionsExecutive function was lower in the physical frailty group, and the possibility of an effect on physical activity was suggested. Based on these results, evaluation of physical frailty can lead to more strategic prevention and treatment by combining physical performance evaluation with cognitive function tests including evaluation of executive function.