Descending pathways in the cervical cord of cats affecting blood pressure and sympathetic activity
Descending pathways in the cervical cord of cats affecting blood pressure and sympathetic activity
复制标题
猫颈髓的下降通路影响血压和交感神经活动
DOI：
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发表时间：
2004
期刊：
影响因子：
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通讯作者：
M. Gabriel
中科院分区：
文献类型：
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作者：
Michael Illert;M. Gabriel
摘要 在 13 只 C2 处脊髓化的猫中，通过单极电刺激（40 μA 或 50 μA）系统地探索了颈脊髓 (SC)，以了解血压 (BP) 和交感神经活动（肾脏或内脏）的反应。交感神经反应和血压反应是从 SC 的广泛区域引发的。背柱内的刺激既不会改变血压，也不会改变交感神经活动（SMA）。
1.增加血压和增强 SMA 的兴奋区域位于外侧索 (LF) 的背侧部分和灰质的 II-VII 层。齿状韧带背侧的刺激在整个刺激期间激活了SMA，并产生了最高的血压增加。2.在腹索、LF的腹侧部分以及背角的顶点和头部的外侧，发现了降低血压和减少SMA的抑制区域。 SMA反应的减少表现出与不同SC区域无关的各种过程。3.兴奋区和抑制区之间的过渡区内的刺激可以相互独立地改变BP和SMA。4.假设刺激的反应表明下行通路的兴奋。讨论了这些通路与控制脊髓交感神经活动的脊髓上系统的联系。
SummaryIn 13 cats spinalized at C2 the cervical spinal cord (SC) was explored systematically by electrical monopolar stimulation (40 μA or 50 μA) for responses of blood-pressure (BP) and sympathetic activity (renal or splanchnic). Sympathetic responses and BP reactions were elicited from extensive regions of the SC. Stimulation within the dorsal column changed neither BP nor sympathetic mass activity (SMA).
1.An excitatory region increasing BP and enhancing SMA was localized in the dorsal part of the lateral funiculus (LF) and in laminae II–VII of the grey matter. Stimulation just dorsal to the dentate ligament activated the SMA during the whole stimulation period and produced the highest BP increases found.2.An inhibitory region decreasing BP and reducing SMA was revealed in the ventral funiculus, in the ventral part of the LF and lateral to the apex and head of the dorsal horn. The reduced SMA responses showed various courses which were not associated with distinct SC regions.3.Stimulation within the transitional zones between excitatory and inhibitory areas could change the BP and SMA independent of one another.4.It is assumed that the responses of stimulation indicate an excitation of descending pathways. The connection of these pathways with supraspinal systems controlling spinal sympathetic activity is discussed.