γ-glutamyltransferase is a Helicobacter pylori virulence factor but is not essential for colonization
γ-glutamyltransferase is a Helicobacter pylori virulence factor but is not essential for colonization
复制标题
DOI：
10.1128/iai.69.6.4168-4173.2001
复制
发表时间：
2001-06-01
影响因子：
3.1
通讯作者：
Youngman, P
中科院分区：
文献类型：
--
作者：
McGovern, KJ;Blanchard, TG;Youngman, P
The contribution of glutamyl transpeptidase (GGT) (gamma -glutamyltransferase [EC 2. 3. 2. 2]) to Helicobacter pylori virulence nias investigated in piglets and mice using GGT-deficient isogenic strains. All animals became colonized. However, the bacterial load,vas significantly lower for mutant bacteria than for parent strains. These results suggest that GGT activity provides an advantage to H. pylori in colonization.
