Effects of HIV voluntary medical male circumcision programs on sexually transmitted infections.
Effects of HIV voluntary medical male circumcision programs on sexually transmitted infections.
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DOI：
10.1097/qco.0000000000000696
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发表时间：
2021-02-01
影响因子：
3.9
通讯作者：
Chasela C
中科院分区：
文献类型：
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作者：
Matoga M;Hosseinipour MC;Jewett S;Hoffman IF;Chasela C
自愿医疗男性包皮环切术（VMMC）对艾滋病毒的保护作用的证据是众所周知的。然而，VMMC对其他性传播感染（STI）的保护作用的证据在不同人群和环境中不一致或很少。本文综述了VMMC对异性恋男性、女性和男男性行为者（MSM）感染和传播其他性传播疾病的影响。最近的研究结果继续有力地支持男性医学包皮环切术对异性恋男性和女性的单纯疱疹病毒2型（HSV-2）、人乳头瘤病毒（HPV）和梅毒感染以及女性细菌性阴道病和滴虫病的获得和传播的保护作用。有新的证据表明，VMMC对异性恋男性获得B型肝炎和生殖支原体感染以及MSM中HSV-2、HPV和梅毒具有保护作用。关于VMMC对获得和传播常见性传播感染的保护作用的证据可用于异性恋男性和女性，但需要更多的证据用于MSM。这项审查支持关于VMMC对性传播感染的保护效益的政策建议。
Evidence of the protective effect of voluntary medical male circumcision (VMMC) against HIV is well established. However, evidence of the protective effect of VMMC against other sexually transmitted infections (STIs) has been inconsistent or scarce across different populations and settings. This review summarizes the current evidence on the effect of VMMC for HIV prevention on acquisition and transmission of other STIs in heterosexual men, women and men who have sex with men (MSM). Recent findings continue to strongly support the protective effect of male medical circumcision against acquisition and transmission of herpes simplex virus type 2 (HSV-2), human papillomavirus (HPV) and syphilis infections in heterosexual men and women, and bacterial vaginosis and trichomoniasis in women. There is emerging evidence on the protective effect of VMMC against acquisition of hepatitis B and Mycoplasma genitalium infections in heterosexual men, and HSV-2, HPV and syphilis in MSM. Evidence on the protective effect of VMMC against acquisition and transmission of common sexually transmitted infections is available for heterosexual men and women but more evidence is required for MSM. This review supports policy recommendations for the protective benefits of VMMC against STIs.