Ultrasonically guided fine‐needle biopsies in neoplastic liver disease: Cytohistologic diagnoses and echo pattern of lesions

Ultrasonically guided fine‐needle biopsies in neoplastic liver disease: Cytohistologic diagnoses and echo pattern of lesions
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超声引导细针活检治疗肿瘤性肝病:细胞组织学诊断和病变回声模式

DOI:
10.1002/1097-0142(19810915)48:6
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发表时间:
1981
期刊:
影响因子:
6.2
通讯作者:
MD P. SCHMITZ
MD P. SCHMITZ
中科院分区:
医学1区
文献类型:
--
作者:
MD W. B. Schwerk;MD P. SCHMITZ

文献摘要

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在超声引导下,对超声疑似局灶性或弥漫性肿瘤性肝病患者进行了60次连续经皮细针抽吸活检,未发生并发症。抽吸样本的评价基于涂片制备的细胞学检查(100%)结合连续切片组织碎片的组织学检查(81.7%)。细胞组织学评估的总体准确率为91.6%,敏感性为92.2%,特异性为88.9%,阳性结果的预测值较高(细胞学97.8%,组织学100%)。超声引导下经皮细针穿刺活检被证明是一种安全、有用和高度准确的技术,用于对疑似恶性的肝脏肿块进行细胞组织学诊断。肝内肿瘤性病变的各种回声模式与细胞类型或肿瘤起源的原发部位之间没有关系。
Sixty consecutive percutaneous fine‐needle aspiration biopsies guided by ultrasound were performed without complications in patients with ultrasonically suspected focal or diffuse neoplastic liver disease. Evaluations of aspirated samples were based on cytologic examination of smear preparations (100%) combined with histologic examination of serial sectioned tissue fragments (81.7%). The overall accuracy rate of cytohistologic evaluations was 91.6% with a sensitivity of 92.2%, a specificity of 88.9%, and a high predictive value of positive results (cytology; 97.8%; histology, 100%). Percutaneous fine‐needle aspiration biopsy guided by sonography proved to be a safe, useful, and highly accurate technique for making cytohistologic diagnoses of hepatic masses suspected of being malignant. No relationship was found between the various echo patterns of intrahepatic neoplastic lesions and cell type or primary site of tumor origin.