Aneurysmal bone cyst - Fine-needle aspiration findings in 23 patients with clinical and radiologic correlation

Aneurysmal bone cyst - Fine-needle aspiration findings in 23 patients with clinical and radiologic correlation
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DOI:
10.1309/vb1m9d9h7qg6l3r4
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发表时间:
2007-11-01
影响因子:
3.5
通讯作者:
Geisinger, Kim R.
Geisinger, Kim R.
中科院分区:
医学4区
文献类型:
--
作者:
Creager, Andrew J.;Madden, Christopher R.;Geisinger, Kim R.

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动脉瘤性骨囊肿(ABC)是一种骨性肿块病变,占原发性骨肿瘤的1%。我们描述了23例ABC,最初通过细针穿刺活检(FNAB)进行评估。4例ABC继发于另一原发肿瘤,6例(26%)抽吸量不足。经FNAB诊断为ABC的12例患者经组织学检查证实为ABC。排除不适合评估的病例,FNAB的准确率为82%。1例细胞学诊断为ABC,随后发现为转移性癌。在另一例中,标本被解释为ABC vs巨细胞瘤;在其余病例中,ABC的诊断更倾向于细胞学诊断。由于非特异性的发现,ABC不能通过FNAB明确诊断。然而,典型的临床和放射学特征,以及富含血液的间充质细胞,含有缺乏明显恶性细胞的抽吸液,强烈提示abc的诊断。
Aneurysmal bone cyst (ABC) is an osseous mass lesion that accounts for 1% of primary bone tumors. We describe 23 cases of ABC initially evaluated by fineneedle aspiration biopsy (FNAB). In 4 cases, the ABC was secondary to another primary tumor Aspirates from 6 cases (26%) were insufficient. Twelve aspirates diagnosed as ABC by FNAB were confirmed as ABC by histologic examination. The accuracy of FNAB was 82% when cases insufficientfor evaluation were excluded. One case diagnosed as ABC cytologically was subsequently found to be metastatic carcinoma. In another, the specimen was interpreted as ABC vs giant cell tumor In the remainder, a diagnosis ofABC was favored cytologically. Owing to the nonspecific findings, ABC cannot be definitively diagnosed by FNAB. However, the presence of typical clinical and radiographic features in conjunction with a blood-rich, mesenchymal cell containing aspirate devoid of overtly malignant cells strongly suggests the diagnosis ofABC.