Variability in the phases of the menstrual cycle
Variability in the phases of the menstrual cycle
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DOI：
10.1111/j.1552-6909.2006.00051.x
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发表时间：
2006-05-01
影响因子：
1.8
通讯作者：
Raviele, K
中科院分区：
文献类型：
--
作者：
Fehring, RJ;Schneider, M;Raviele, K
目的：确定健康、有规律的周期妇女月经周期各阶段的变异性。设计：一项使用生物标志物估计月经周期参数的新数据集的前瞻性描述性研究。参与者：141名健康女性(平均年龄29岁)，她们使用电子生育监测器监测3至13个月经周期，产生1,060个可用周期。测量和结果：月经周期长度、卵泡期、生育期、黄体期和月经期的变异性。结果：平均总周期为28.9天(SD=3.4)，95%的周期在22~36天之间。在42.5%的妇女中观察到周期内变异性大于7天。95%的受试者在第4天到第23天之间有6天的生育期，但只有25%的受试者在第10天到第17天之间有所有的受孕期。结论：在经常骑车的妇女中，月经周期的各阶段有相当大的正常变异性。卵泡期对这种可变性的贡献最大。
Objective: To determine variability in the phases of the menstrual cycle among healthy, regularly cycling women.Design: A prospective descriptive study of a new data set with biological markers to estimate parameters of the menstrual cycles.Participants: One hundred forty one healthy women (mean age 29 years) who monitored 3 to 13 menstrual cycles with an electronic fertility monitor and produced 1,060 usable cycles of data.Measures and Outcomes: Variability in the length of the menstrual cycle and of the follicular, fertile, and luteal phases, and menses. The estimated day of ovulation and end of the fertile phase was the peak fertility reading on the monitor (i.e., the urinary luteinizing hormone surge).Results: Mean total length was 28.9 days (SD= 3.4) with 95% of the cycles between 22 and 36 days. Intracycle variability of greater than 7 days was observed in 42.5% of the women. Ninety-five percent of the cycles had all 6 days of fertile phase between days 4 and 23, but only 25% of participants had all days of the fertile phase between days 10 and 17.Conclusions: Among regularly cycling women, there is considerable normal variability in the phases of the menstrual cycle. The follicular phase contributes most to this variability.