UJI EFEK ANTELMINTIK EKSTRAK ETANOL BIJI PINANG (ARECA CATECHU) TERHADAP CACING ASCARIS LUMBRICOIDES DAN ASCARIDIA GALLI SECARA IN VITRO
UJI EFEK ANTELMINTIK EKSTRAK ETANOL BIJI PINANG (ARECA CATECHU) TERHADAP CACING ASCARIS LUMBRICOIDES DAN ASCARIDIA GALLI SECARA IN VITRO
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UJI EFEK ANTELMINTIK EKSTRAK ETANOL BIJI PINANG (ARECA CATECHU) TERHADAP CACING ASCARIS LUMBRICOIDES DAN ASCARIDIA GALLI SECARA 体外
DOI：
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发表时间：
2013
期刊：
影响因子：
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通讯作者：
Novel Kojong
中科院分区：
文献类型：
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作者：
Debra Tiwow;Widdhi Bodhi;Novel Kojong
槟榔（Areca catechu）是民间常用药，具有驱虫活性.驱虫药是用来减少或消灭人体或动物体内蠕虫的药物。本研究旨在探讨槟榔醇提物对蛔虫和鸡蛔虫的驱肠虫活性，并确定槟榔醇提物作为驱肠虫剂的有效浓度。本实验以槟榔醇提物为研究对象，分别以10%、20%、30%的浓度进行萃取。每小时观察一次蠕虫的死亡率和麻痹率，持续12小时。所得数据用方差分析进行统计学处理。进行回归分析以确定PC50和LC50。结果表明，槟榔醇提物对人体蛔虫和鸡蛔虫具有体外驱虫作用。对蛔虫的PC_（50）为27.12%，对鸡蛔虫的LC_（50）为27.11%。关键词：驱虫药，槟榔醇提物，蛔虫，鸡蛔虫
Betel nut (Areca catechu) known as folks medicine that possess anthelmintic activity. Anthelmintic were used to reduce or eliminate the worm in human or animal body. The aims of this research were to find out anthelmintic activity of ethanol extract of betel nut against Ascaris lumbricoides and Ascaridia galli, and to determine efective concentration of ethanol extract of betel nut as an anthelmintic. This assay using ethanol extracts of betel nut with concentration of 10%, 20%, and 30%. Mortality and paralysis percent of worms observed every hour for 12 hours. Obtained data were analyzed by ANOVA. Regression analysis was conducted to determine PC50 and LC50. The result show that ethanol extract of betel nut possess an in vitro anthelmintic against Ascaris lumbricoides and Ascaridia galli. PC50 values obtained in Ascaris lumbricoides was 27.12%, and LC50 values obtained in Ascaridia galli was 27.11% on worm for 12 hours. Keywords : Anthelmintic, ethanol extract of betel nut (Areca catechu), Ascaris lumbricoides, Ascaridia galli