Perfusion-weighted imaging defects during spontaneous migrainous aura
Perfusion-weighted imaging defects during spontaneous migrainous aura
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DOI：
10.1002/ana.410430108
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发表时间：
1998-01-01
影响因子：
11.2
通讯作者：
Moskowitz, MA
中科院分区：
文献类型：
--
作者：
Cutrer, FM;Sorensen, AG;Moskowitz, MA
在四名偏头痛患者的自发视觉先兆期间进行了灌注和扩散加权磁共振成像。在受影响的视觉半视野对侧的枕叶皮质灰质中观察到相对脑血流量（减少 16-53%）、脑血容量（减少 6-33%）和组织平均通过时间（增加 10-54%）的变化。当患者出现症状时或视觉症状消退后但头痛发作之前，没有观察到表观弥散系数的变化。功能性磁共振成像可以成为一种有用的非侵入性工具，用于研究先兆偏头痛自发发作期间的血流动力学变化。
Perfusion-and diffusion-weighted magnetic resonance imaging was performed during spontaneous visual auras in four migraineurs. Alterations in relative cerebral blood flow (16-53% decrease), cerebral blood volume (6-33% decrease), and tissue mean transit time (10-54% increase) were observed in the gray matter of occipital cortex contralateral to the affected visual hemifield. No changes in the apparent diffusion coefficient were observed either while the patients were symptomatic or after resolution of the visual symptoms but before the onset of headache. Functional magnetic resonance imaging can be a useful noninvasive tool to study hemodynamic changes during spontaneous attacks of migraine with aura.