Mantle irradiation in Hodgkin's disease. An analysis of technique, tumor eradication, and complications
Mantle irradiation in Hodgkin's disease. An analysis of technique, tumor eradication, and complications
复制标题
霍奇金病的地幔照射。
作者：
R. Carmel;H. Kaplan
对377例接受过外套膜照射但未计划化疗的霍奇金病患者的治疗和随访记录进行分析，结果显示总体膈上复发率为21%。治疗并发症包括症状性肺放射反应（20%）、心包炎（13%）、Lhermitte征（15%）和甲状腺功能障碍（13%）。在2500至3500拉德后增加隆突下阻滞，并在选定的患者中使用薄肺阻滞技术，在不牺牲局部控制的情况下，将肺部和心包并发症的发生率降低至5%以下。进一步修改的技术和治疗政策进行了讨论，以提高治疗率。
Analysis of the treatment and follow‐up records of 377 Hodgkin's disease patients who received mantle irradiation but no planned chemotherapy reveals an overall supradiaphragmatic relapse rate of 21%. Complications of treatment included symptomatic pulmonary radiation reaction (20%), pericarditis (13%), Lhermitte's sign (15%), and thyroid dysfunction (13%). The addition of a subcarinal block after 2500 to 3500 rads and the use of the thin lung block technique in selected patients have reduced the incidence of pulmonary and pericardial complications to less than 5% without sacrificing local control. Further modifications in technique and treatment policy are discussed in terms of improving the therapeutic ratio.
影响因子：
11.2
作者：
P. Carbone;H. Kaplan;K. Musshoff;D. Smithers;M. Tubiana
通讯作者：
P. Carbone;H. Kaplan;K. Musshoff;D. Smithers;M. Tubiana