Development and Validation of a Photonumeric Scale for Evaluation of Static Horizontal Forehead Lines
Development and Validation of a Photonumeric Scale for Evaluation of Static Horizontal Forehead Lines
复制标题
DOI：
10.1097/dss.0000000000000855
复制
发表时间：
2016-10-01
影响因子：
2.4
通讯作者：
Dill, Sara
中科院分区：
文献类型：
--
作者：
Carruthers, Alastair;Donofrio, Lisa;Dill, Sara
背景：在实践和临床研究中，需要一个有效的量表来客观和可重复地比较治疗前后的静态额头纹。目的描述5点光子学艾尔建额线量表的开发和验证。方法制定艾尔建额纹量表，包括每个等级的评估指南、语言描述、变形图像和真实受试者图像。1分评分差异的临床意义是通过对多个图像对的回顾来评估的，这些图像对代表着不同程度的差异。在一项活体受试者验证研究（N = 295）中，评估了被测者之间和被测者内部的信度，该研究在间隔3周的两个疗程中完成。结果>= 1分的评分差异为临床显著性差异（平均[95%置信区间]绝对评分差异，临床不同影像对为1.06[0.91-1.21]，无临床不同影像对为0.38[0.26-0.51]）。两个活体受试者验证会话之间的内部一致性几乎是完美的（平均加权kappa = 0.87）。在第二次评分期间，评分者之间的一致性几乎是完美的（0.86，主要终点）。结论艾尔建额纹量表是一种经过验证和可靠的评估静态水平额纹的量表。
BACKGROUND A validated scale is needed for objective and reproducible comparisons of static forehead lines before and after treatment in practice and clinical studies.OBJECTIVE To describe the development and validation of the 5-point photonumeric Allergan Forehead Lines Scale.METHODS The Allergan Forehead Lines Scale was developed to include an assessment guide, verbal descriptors, morphed images, and real subject images for each scale grade. The clinical significance of a 1-point score difference was evaluated in a review of multiple image pairs representing varying differences in severity. Interrater and intrarater reliability was evaluated in a live-subject validation study (N = 295) completed during 2 sessions occurring 3 weeks apart.RESULTS A difference of >= 1 point on the scale was shown to reflect a clinically significant difference (mean [95% confidence interval] absolute score difference, 1.06 [0.91-1.21] for clinically different image pairs and 0.38 [0.26-0.51] for not clinically different pairs). Intrarater agreement between the 2 live-subject validation sessions was almost perfect (mean weighted kappa = 0.87). Interrater agreement was almost perfect during the second rating session (0.86, primary end point).CONCLUSION The Allergan Forehead Lines Scale is a validated and reliable scale for physician rating of static horizontal forehead lines.