Effect of Sn addition on the mechanical properties and bio-corrosion behavior of cytocompatible Mg-4Zn based alloys
Effect of Sn addition on the mechanical properties and bio-corrosion behavior of cytocompatible Mg-4Zn based alloys
复制标题
Sn添加对细胞相容性Mg-4Zn基合金力学性能和生物腐蚀行为的影响
DOI：
10.1016/j.jma.2019.02.002
复制
发表时间：
2019-03-01
影响因子：
17.6
通讯作者：
Guo, Shengfeng
中科院分区：
文献类型：
--
作者：
Jiang, Weiyan;Wang, Jingfeng;Guo, Shengfeng
系统研究了挤压态Mg-4 Zn合金添加Sn后的力学性能和生物腐蚀行为。Mg-4 Zn合金中加入少量Sn，可使合金的力学性能略有提高，并可显著控制其生物腐蚀速率。Sn以SnO/SnO_2的形式参与外层膜的形成，起到了抗生物腐蚀的作用。特别是Mg-4 Zn-1.5Sn合金，其失重速率为0.45 mm/y，析氢速率为0.099 mL/cm（2）/天，对MC 3 T3-E1细胞的细胞毒性等级为0。Mg-4 Zn-1.5Sn合金具有良好的细胞相容性、良好的力学性能和较低的生物腐蚀率，是一种很有前途的可生物降解骨科植入物镁合金。(C)2019由Elsevier B. V.代表重庆大学出版。
The mechanical properties and bio-corrosion behaviors of as-extruded Mg-4Zn alloys after Sn addition were investigated, systematically. A small amount of Sn addition to Mg-4Zn alloy slightly improved the mechanical properties for solid solution strengthening, and significantly controlled the bio-corrosion rates. Sn participating in the outer layer film formation as SnO/SnO2 resisted the bio-corrosion proceeding. Especially, Mg-4Zn-1.5Sn alloy, with a weight loss rate of 0.45 mm/y and hydrogen evolution rate of 0.099 mL/cm(2)/day, showed cytotoxicity grade of 0 to MC3T3-E1 cells. The perfect alliance of cytocompatibility, suitable mechanical properties and low bio-corrosion rate demonstrates that this Mg-4Zn-1.5Sn alloy is a promising biodegradable magnesium alloy for orthopedic implants. (C) 2019 Published by Elsevier B.V. on behalf of Chongqing University.