SYNTHESIS AND TURNOVER OF RIBOSOMAL-PROTEINS IN ABSENCE OF 60S SUBUNIT ASSEMBLY IN SACCHAROMYCES-CEREVISIAE
SYNTHESIS AND TURNOVER OF RIBOSOMAL-PROTEINS IN ABSENCE OF 60S SUBUNIT ASSEMBLY IN SACCHAROMYCES-CEREVISIAE
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DOI：
10.1007/bf00268670
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发表时间：
1977-01-01
期刊：
影响因子：
--
通讯作者：
WARNER, JR
中科院分区：
文献类型：
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作者：
GORENSTEIN, C;WARNER, JR
对一株温度敏感的酵母菌的核糖体蛋白的合成和稳定性进行了测定，该菌株在限制性温度下对27S核糖体前体RNA的加工具有特异性阻断作用。在没有60S核糖体亚单位组装的情况下，所有研究的核糖体蛋白的合成仍在继续。60S亚基的蛋白质不能积累并迅速降解。
The synthesis and stability of ribosomal proteins in a temperature sensitive strain of yeast, which at the restrictive temperature is specifically blocked in the processing of 27S ribosomal precursor RNA, was measured. In the absence of 60S ribosomal subunit assembly, the synthesis of all ribosomal proteins studied continued. The proteins of the 60S subunit fail to accumulate and are rapidly degraded.