Do Women With Atrial Fibrillation Experience More Severe Strokes?: Results From the Austrian Stroke Unit Registry
Do Women With Atrial Fibrillation Experience More Severe Strokes?: Results From the Austrian Stroke Unit Registry
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DOI：
10.1161/strokeaha.116.015900
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发表时间：
2017-03-01
期刊：
影响因子：
8.3
通讯作者：
Knoflach, Michael
中科院分区：
文献类型：
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作者：
Lang, Clemens;Seyfang, Leonhard;Knoflach, Michael
背景和目的 与心房颤动 (AF) 相关的缺血性中风比其他原因引起的缺血性中风更为严重。我们的目标是研究这种背景下潜在的性别影响。 方法 在这项横断面研究中，2003 年 3 月至 2016 年 1 月期间，纳入了奥地利卒中病房登记处的 74425 名患有急性缺血性卒中的成人。在 63563 名患者中，美国国立卫生研究院卒中量表关于入院卒中病房、是否存在房颤、血管危险因素和合并症的数据是完整的。通过多元回归模型进行分析。结果中风严重程度总体上随着年龄的增长而增加。房颤相关的中风比其他原因引起的中风更严重。仅在患有房颤的中风患者中观察到中风严重程度的性别相关差异。美国国立卫生研究院卒中量表评分中位数 (Q(25),(75)) 女性为 9 (4,17)，男性为 6 (3,13)（P
Background and Purpose Ischemic strokes associated with atrial fibrillation (AF) are more severe than those of other cause. We aim to study potential sex effects in this context.Methods In this cross-sectional study, 74425 adults with acute ischemic stroke from the Austrian Stroke Unit Registry were included between March 2003 and January 2016. In 63563 patients, data on the National Institutes of Health Stroke Scale on admission to the stroke unit, presence of AF, vascular risk factors, and comorbidities were complete. Analysis was done by a multivariate regression model.Results Stroke severity in general increased with age. AF-related strokes were more severe than strokes of other causes. Sex-related differences in stroke severity were only seen in stroke patients with AF. Median (Q(25),(75)) National Institutes of Health Stroke Scale score points were 9 (4,17) in women and 6 (3,13) in men (P