Treponema denticola interactions with host proteins.
Treponema denticola interactions with host proteins.
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DOI：
10.3402/jom.v4i0.9929
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发表时间：
2012-01-01
影响因子：
4.5
通讯作者：
Fenno, J Christopher
中科院分区：
文献类型：
--
作者：
Fenno, J Christopher
口腔密螺旋体属，最显著的是T.齿垢与人类牙周病的破坏性作用有关。T.本文综述了齿垢锥虫与宿主蛋白质的关系，重点介绍了齿垢锥虫表面表达和分泌蛋白的特性。参与与宿主细胞、细胞外基质成分和先天免疫系统成分相互作用的齿垢。
Oral Treponema species, most notably T. denticola, are implicated in the destructive effects of human periodontal disease. Progress in the molecular analysis of interactions between T. denticola and host proteins is reviewed here, with particular emphasis on the characterization of surface-expressed and secreted proteins of T. denticola involved in interactions with host cells, extracellular matrix components, and components of the innate immune system.