Chiral symmetry breaking during the self-assembly of monolayers from achiral purine molecules
Chiral symmetry breaking during the self-assembly of monolayers from achiral purine molecules
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非手性嘌呤分子单层自组装过程中手性对称性破缺
DOI：
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发表时间：
1996
影响因子：
3.9
通讯作者：
G. B. Petersen
中科院分区：
文献类型：
--
作者：
S. Sowerby;W. Heckl;G. B. Petersen
利用扫描隧道显微镜研究了嘌呤碱基腺嘌呤在天然矿物蒙脱石和人工晶体高取向热解石墨表面的分子自组装形成的二维吸附质的结构。虽然形成腺嘌呤，这是非手性的，所观察到的吸附物表面结构是对映异构体的钙钛矿。这一现象表明了一种机制，用于引入本地化的手性对称性破缺的自发结晶这些prebiotically可用的分子在无机表面上，并可能有一些生物分子的光学不对称性的起源中的作用。嘌呤嘧啶阵列组装在自然发生的矿物表面可能作为生物分子组装可能的模板的可能性进行了讨论。
Scanning tunneling microscopy was used to investigate the structure of the two-dimensional adsorbate formed by molecular self-assembly of the purine base, adenine, on the surfaces of the naturally occurring mineral molybdenite and the synthetic crystal highly oriented pyrolytic graphite. Although formed from adenine, which is achiral, the observed adsorbate surface structures were enantiomorphic on molybdenite. This phenomenon suggests a mechanism for the introduction of a localized chiral symmetry break by the spontaneous crystallization of these prebiotically available molecules on inorganic surfaces and may have some role in the origin of biomolecular optical asymmetry. The possibility that purine-pyrimidine arrays assembled on naturally occurring mineral surfaces might act as possible templates for biomolecular assembly is discussed.