Distribution of axial length, anterior chamber depth, and corneal curvature in an aged population in South China.
Distribution of axial length, anterior chamber depth, and corneal curvature in an aged population in South China.
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DOI：
10.1186/s12886-016-0221-5
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发表时间：
2016-05-01
影响因子：
2
通讯作者：
Chen W
中科院分区：
文献类型：
--
作者：
Chen H;Lin H;Lin Z;Chen J;Chen W
眼生物测量对于白内障和眼前节手术的术前评估非常重要。本研究的目的是调查中国老年人群的正常眼生物特征参数及其相关性。这是一项横断面观察性研究。从2013年到2014年，我们在中国广州招募了50岁或以上的居民。在1,117名参与者中，1,015只有晶状体右眼的数据被用于分析。使用IOL Master测量包括眼轴长度（AL）、前房深度（ACD）和角膜曲率（K）在内的眼部参数。平均AL、ACD和K分别为23.48 mm [95%置信区间（CI），23.40-23.55]、3.03 mm（CI，3.01-3.05）和44.20 mm（CI，44.11-44.29）。在男性受试者中观察到ACD随年龄平均降低（P = 0.002），但在女性受试者中未观察到（P = 0.558）。与女性受试者相比，男性受试者的AL（23.68 mm vs 23.23 mm，P < 0.001）、ACD（3.13 mm vs 2.95 mm，P < 0.001）和Ks（43.85 D vs 44.50 D，P < 0.001）显著更长。眼轴延长的眼角膜更平坦（r =-0.437，P < 0.001），前房更深（r = 0.652，P < 0.001）。ACD与K相关（r =-0.266，P < 0.001）。这些数据提供了中国南方人群使用IOL Master时AL、ACD和K的标准值。该中国队列中的AL大于新加坡华人中观察到的AL，但小于马来西亚和高加索人中观察到的AL。中国人的ACD比其他一些种族群体要浅。年龄和性别是中国南方老年人群中最一致的眼部生物学预测因素。
Ocular biometry is important for preoperative assessment in cataract and anterior segment surgery. The purpose of this study was to investigate normative ocular biometric parameters and their associations in an older Chinese population. This was a cross-sectional observational study. From 2013 to 2014, we recruited inhabitants aged 50 years or older in Guangzhou, China. Among 1,117 participants in the study, data from 1,015 phakic right eyes were used for analyses. Ocular parameters including axial length (AL), anterior chamber depth (ACD), and corneal curvature (K) were measured using an IOL Master. The mean AL, ACD, and K were 23.48 mm [95 % confidence interval (CI), 23.40–23.55], 3.03 mm (CI, 3.01–3.05), and 44.20 mm (CI, 44.11–44.29), respectively. A mean reduction in ACD with age was observed (P = 0.002) in male subjects but not in female subjects (P = 0.558). Male subjects had significantly longer ALs (23.68 mm versus 23.23 mm, P < 0.001), deeper ACDs (3.13 mm versus 2.95 mm, P < 0.001), and flatter Ks (43.85D versus 44.50 D, P < 0.001) than female subjects. Eyes with axial elongation had a flatter cornea (r = −0.437, P < 0.001) and a deeper anterior chamber (r = 0.652, p < 0.001). The ACD was correlated with K (r = −0.266, P < 0.001). These data provide normative values for AL, ACD, and K using the IOL Master for a population in South China. The AL in this Chinese cohort was greater than that observed in the Singaporean Chinese but smaller than that observed in Malaysia and for Caucasians. The Chinese have a shallower ACD than some other racial groups. Age and sex were the most consistent predictors of ocular biometry in the older population from South China.