Clinical Predictors of Sensorineural Hearing Loss and Cognitive Outcome in Infants with Symptomatic Congenital Cytomegalovirus Infection.
Clinical Predictors of Sensorineural Hearing Loss and Cognitive Outcome in Infants with Symptomatic Congenital Cytomegalovirus Infection.
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DOI：
10.1097/inf.0000000000001194
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发表时间：
2016-08
期刊：
影响因子：
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通讯作者：
Ross SA
中科院分区：
文献类型：
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作者：
Pinninti SG;Rodgers MD;Novak Z;Britt WJ;Fowler KB;Boppana SB;Ross SA
本研究的目的是确定新生儿临床表现预测不良临床结果的婴儿有症状的先天性巨细胞病毒（cCMV）感染。在160名婴儿中，与有一过性发现或仅有点状皮疹的婴儿相比，有中枢神经系统（CNS）受累的儿童有更多的感音神经性听力损失（SNHL）（p = 0.0007）和IQ ≤ 70（p < 0.0001）。
The objective of this study was to determine newborn clinical findings predictive of adverse clinical outcomes in infants with symptomatic congenital cytomegalovirus (cCMV) infection. Of 160 infants, significantly more children with central nervous system (CNS) involvement had sensorineural hearing loss (SNHL) (p = 0.0007) and an IQ ≤ 70 (p < 0.0001) compared with infants with transient findings or only a petechial rash.