Access and outcomes among minority transplant patients, 1999-2008, with a focus on determinants of kidney graft survival.
Access and outcomes among minority transplant patients, 1999-2008, with a focus on determinants of kidney graft survival.
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DOI：
10.1111/j.1600-6143.2009.03009.x
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发表时间：
2010-04
期刊：
影响因子：
--
通讯作者：
Leichtman AB
中科院分区：
文献类型：
--
作者：
Fan PY;Ashby VB;Fuller DS;Boulware LE;Kao A;Norman SP;Randall HB;Young C;Kalbfleisch JD;Leichtman AB
随着国家对公平医疗保健的兴趣日益增加，一些研究描述了少数民族患者在获得实体器官移植方面的差距。相比之下，对特定种族和民族人群患者之间移植后结局的差异知之甚少。在本文中，我们回顾了获得实体器官移植和移植后结果的趋势，器官类型，种族和民族。此外，我们还分析了导致肾移植结果中种族/民族差异的因素类别。等待名单上的候选人中少数人获得移植的差异正在改善，但对于那些等待肾脏，肾脏和胰腺以及肠移植的人来说，这种差异仍然存在。一般来说，亚洲人和西班牙裔/拉丁美洲人的实体器官移植受者的移植物和患者存活率最高，白人居中，非洲裔美国人最低。尽管人种/种族组之间结局的大部分差异可以通过调整患者特征来解释，但仍存在重要的观察到的差异。年龄和移植前透析暴露的持续时间是最重要的生存决定因素，在一项研究中，中心相关变量与患者相关变量对肾移植结局的相对影响。
Coincident with an increasing national interest in equitable health care, a number of studies have described disparities in access to solid organ transplantation for minority patients. In contrast, relatively little is known about differences in posttransplant outcomes between patients of specific racial and ethnic populations. In this paper, we review trends in access to solid organ transplantation and posttransplant outcomes by organ type, race and ethnicity. In addition, we present an analysis of categories of factors that contribute to the racial/ethnic variation seen in kidney transplant outcomes. Disparities in minority access to transplantation among wait-listed candidates are improving, but persist for those awaiting kidney, simultaneous kidney and pancreas and intestine transplantation. In general, graft and patient survival among recipients of solid organ transplants is highest for Asians and Hispanic/Latinos, intermediate for whites and lowest for African Americans. Although much of the difference in outcomes between racial/ethnic groups can be accounted for by adjusting for patient characteristics, important observed differences remain. Age and duration of pretransplant dialysis exposure emerge as the most important determinants of survival in an investigation of the relative impact of center-related versus patient-related variables on kidney graft outcomes.
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影响因子：
6.2
作者：
Israni, Ajay K.;Li, Na;Feldman, Harold I.
通讯作者：
Feldman, Harold I.
影响因子：
13.2
作者：
Isaacs, RB;Lobo, PI;Pruett, TL
通讯作者：
Pruett, TL
DOI：
10.1002/lt.500040606
发表时间：
1998-11-01
期刊：
LIVER TRANSPLANTATION AND SURGERY
影响因子：
--
作者：
Eckhoff, DE;McGuire, BM;Bynon, S
通讯作者：
Bynon, S
影响因子：
158.5
作者：
Epstein, AM;Ayanian, JZ;Conti, RM
通讯作者：
Conti, RM
影响因子：
6.2
作者：
Girnita, Diana M.;Webber, Steven A.;Zeevi, Adriana
通讯作者：
Zeevi, Adriana