Behavioral Microbiomics: A Multi-Dimensional Approach to Microbial Influence on Behavior.
Behavioral Microbiomics: A Multi-Dimensional Approach to Microbial Influence on Behavior.
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DOI：
10.3389/fmicb.2015.01359
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发表时间：
2015
影响因子：
5.2
通讯作者：
Simpson SJ
中科院分区：
文献类型：
--
作者：
Wong AC;Holmes A;Ponton F;Lihoreau M;Wilson K;Raubenheimer D;Simpson SJ
微生物作为动物系统的一部分的作用在历史上一直是动物生活史中被低估的一个方面。最近，有证据表明微生物对动物行为有广泛的影响。阐明宿主-微生物相互作用和行为之间的复杂关系需要扩展的生态视角，涉及宿主，微生物组和环境;结合起来，被称为holobiont。我们开始从宿主-寄生虫相互作用的文献中寻求见解，然后扩展到考虑微生物群落成员之间的相互作用网络。环境的一个核心方面是宿主营养。我们描述了如何使用称为营养几何的综合框架来研究营养环境，宿主和微生物组的代谢和行为反应之间的相互作用，该框架集成并映射多维营养摄入空间中宿主和微生物反应的多个方面。
The role of microbes as a part of animal systems has historically been an under-appreciated aspect of animal life histories. Recently, evidence has emerged that microbes have wide-ranging influences on animal behavior. Elucidating the complex relationships between host–microbe interactions and behavior requires an expanded ecological perspective, involving the host, the microbiome and the environment; which, in combination, is termed the holobiont. We begin by seeking insights from the literature on host–parasite interactions, then expand to consider networks of interactions between members of the microbial community. A central aspect of the environment is host nutrition. We describe how interactions between the nutrient environment, the metabolic and behavioral responses of the host and the microbiome can be studied using an integrative framework called nutritional geometry, which integrates and maps multiple aspects of the host and microbial response in multidimensional nutrient intake spaces.