Acute biliary pancreatitis: diagnosis and treatment.

Acute biliary pancreatitis: diagnosis and treatment.
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DOI:
10.4103/1319-3767.54740
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发表时间:
2009-07-01
期刊:
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
影响因子:
--
通讯作者:
Hazem, Zakaria M
Hazem, Zakaria M
中科院分区:
其他
文献类型:
--
作者:
Hazem, Zakaria M

文献摘要

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胆结石是急性胰腺炎(AP)的最常见原因,在世界范围内,这是一种潜在的危及生命的疾病。急性胰腺炎的发病机制尚未完全清楚。实验室和放射检查对诊断和预后预测至关重要。基于放射学发现和血清学炎症标志物的评分系统已被提议作为疾病严重程度的更好预测指标。早期内镜逆行胰胆管造影(ERCP)对胆石性胰腺炎患者是有益的。腹腔镜胆囊切除术术前内镜胆总管清理推荐作为治疗急性胆源性胰腺炎的选择。胆源性胰腺炎的ERCP后胆囊切除术的时机根据胰腺炎的严重程度而有明显的不同。
Gallstones are the commonest cause of acute pancreatitis (AP), a potentially life-threatening condition, worldwide. The pathogenesis of acute pancreatitis has not been fully understood. Laboratory and radiological investigations are critical for diagnosis as well prognosis prediction. Scoring systems based on radiological findings and serologic inflammatory markers have been proposed as better predictors of disease severity. Early endoscopic retrograde cholangiopancreatography (ERCP) is beneficial in a group of patients with gallstone pancreatitis. Laparoscopic cholecystectomy with preoperative endoscopic common bile duct clearance is recommended as a treatment of choice for acute biliary pancreatitis. The timing of cholecystectomy, following ERCP, for biliary pancreatitis can vary markedly depending on the severity of pancreatitis.