Association between lower urinary tract symptoms and sexual dysfunction assessed using the core lower urinary tract symptom score and International index of erectile function-5 questionnaires

Association between lower urinary tract symptoms and sexual dysfunction assessed using the core lower urinary tract symptom score and International index of erectile function-5 questionnaires
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DOI:
10.3109/13685538.2011.646342
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发表时间:
2012-06-01
期刊:
影响因子:
2.6
通讯作者:
Homma, Yukio
Homma, Yukio
中科院分区:
医学4区
文献类型:
--
作者:
Nakamura, Masaki;Fujimura, Tetsuya;Homma, Yukio

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目的:应用下尿路核心症状评分(CLSS)和勃起功能障碍国际指数(IIEF)-5问卷,探讨下尿路症状(LUTS)与勃起功能障碍(ED)之间的关系。方法:220名连续接受治疗的男性完成了国际前列腺症状评分(IPSS)、CLSS和IIEF-5问卷调查。临床诊断为良性前列腺增生症(BPH,n=58)、前列腺癌(n=51)、前列腺炎(n=28)、膀胱过度活动(OAB湿,n=16)、其他诊断(n=39)和正常对照组(n=28)。对IIEF-5低分进行简单统计和预测性检验。结果:IIEF-5总分与IPSS和CLSS问卷呈显著正相关(p=0.0001)。在IPSS和CLSS症状中,除日间频率和排空不全外,其他因素与IIEF-5总分显著相关。多元回归模型显示夜尿和尿痛是导致IIEF-5评分偏低的独立因素。结论:尿路疼痛是勃起功能障碍的独立因素。使用CLSS问卷提取疼痛症状可能有助于评估有盆腔健康问题的男性的LUTS。
Objective: The aim of this study is to assess the association between lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) using the Core Lower Urinary Tract Symptom Score (CLSS) and the International Index of Erectile Dysfunction (IIEF)-5 questionnaires. Methods: A total of 220 consecutive treatment-naive men completed the International Prostate Symptom Score (IPSS), CLSS, and IIEF-5 questionnaires. The clinical diagnoses were benign prostate hyperplasia (BPH, n = 58), prostatic cancer (n = 51), prostatitis (n = 28), overactive bladder wet (OAB wet, n = 16), other diagnoses (n = 39), and controls (n = 28). Simple statistics and predictability of low IIEF-5 score were examined. Results: The total IIEF-5 score significantly correlated with both the IPSS and CLSS questionnaires (p = 0.0001). Among IPSS and CLSS symptoms, factors other than daytime frequency and incomplete emptying showed significant correlation with the total IIEF-5 score. A multivariate regression model indicated nocturia and urethral pain as independent factors for low IIEF-5 scores. Conclusion: Urethral pain was identified as an independent factor for erectile dysfunction. The extraction of pain symptoms using CLSS questionnaire may be useful to evaluate LUTS in men with pelvic health problems.