The polled locus maps to BTA1 in a Bos indicus x Bos taurus cross
The polled locus maps to BTA1 in a Bos indicus x Bos taurus cross
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DOI：
10.1093/oxfordjournals.jhered.a022975
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发表时间：
1996-03-01
影响因子：
3.1
通讯作者：
Taylor, JF
中科院分区：
文献类型：
--
作者：
Brenneman, RA;Davis, SK;Taylor, JF
利用安格斯（Bos taurus）和婆罗门（Bos indicus）亲本及其60个亲本和祖父母的209个正反交和F2代胚胎移植后代，在牛1号染色体遗传图谱上定位了无角表型的基因座（POLL）。在1岁时对后代的无角、有角和有角表型进行评分，并在20月龄屠宰时进行颅骨解剖后再次进行评分。表型频率与性别无关。POLL和13个微卫星位点的142个信息减数分裂，平均每个位点有267个信息减数分裂，构建了一张124.6cM的遗传图谱，平均间隔为9.6cM。在区分scurred和有角的表型之间的困难表明，括号标记将是必不可少的精炼模型的有角的，scurred，和无角表型的遗传和有效的标记辅助选择（MAS）无角。
Two hundred and nine reciprocal back-cross and F2progeny produced by embryo transfer from Angus (Bos taurus) and Brahman (Bos indicus) parents and their 60 parents and grandparents were utilized to localize the locus (POLL) responsible for the polled phenotype in a genetic map of bovine chromosome 1. Progeny were scored for polled, scurred, and horned phenotypes at 1 year of age and again following skull dissection at slaughter at 20 months of age. Phenotype frequencies were independent of gender. One hundred and forty-two informative meioses forPOLLand 13 microsatellite loci with an average of 267 informative meioses per locus contributed to a genetic map spanning 124.6 cM with an average interval of 9.6 cM.POLLmapped proximal to the centromere and 4.9 cM fromTGLA49supporting a previous study that employed two anonymous microsatellites. Difficulties in discriminating between scurred and horned phenotypes indicate that bracketing markers will be essential for refining the model for inheritance of the horned, scurred, and polled phenotypes and for effective marker assisted selection (MAS) for polled.