Induction of Decidua-Placental Hemorrhage in Mice by the Endotoxins of Certain Gram-Negative Bacteria
Induction of Decidua-Placental Hemorrhage in Mice by the Endotoxins of Certain Gram-Negative Bacteria
复制标题
某些革兰氏阴性菌内毒素诱导小鼠蜕膜胎盘出血
DOI：
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发表时间：
1943
期刊：
影响因子：
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通讯作者：
C. Bjerknes
中科院分区：
文献类型：
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作者：
P. A. Zahl;C. Bjerknes
含内毒素的福氏副杆菌志贺氏菌、鼠伤寒沙门氏菌和红红螺旋菌提取物腹腔注射妊娠12 - 18天的小鼠，可引起胎盘蜕膜出血，导致流产或胚胎吸收。指出革兰氏阴性菌内毒素引起的蜕膜-胎盘出血可能与植入性肿瘤在给予革兰氏阴性菌内毒素后引起的出血属于同一类生理作用。
Summary Endotoxin-containing extracts of Shigella paradysenterie Flexner, Salmonella typhimurium, and Rhodospirillum rubrum when injected intraperitoneally into mice pregnant from 12 to 18 days induce decidua-placental hemorrhage which results either in abortion or resorption of the embryos. It is pointed out that such decidua-placental hemorrhage induced by the endo-toxins of gram-negative bacteria may fall into the same class of physiological action as hemorrhage induced in implanted tumors following administration of endotoxins of gram-negative bacteria.