[Cerebellar ataxia due to hypothyroidism in adults (case report)].
[Cerebellar ataxia due to hypothyroidism in adults (case report)].
复制标题
成人甲状腺功能减退症所致小脑性共济失调（病例报告）。
DOI：
10.1055/s-0028-1106608
复制
发表时间：
1975
影响因子：
0.6
通讯作者：
F. Regli
中科院分区：
文献类型：
--
作者：
C. Hammar;F. Regli
小脑性共济失调被诊断为一个62岁的妇女，其体征消退几乎完全在六个星期内治疗甲状腺素和三碘甲状腺原氨酸。小脑共济失调与甲状腺功能减退症的原因仍然不明。小脑没有典型的形态学变化。据推测，甲状腺，特定的代谢因素是负责，其中包括已经存在的非特异性小脑变化。预后很好。另一方面，先天性甲状腺功能减退导致的小脑共济失调具有典型的小脑组织学改变，除非出生后立即开始甲状腺治疗，否则预后非常差。
Cerebellar ataxia was diagnosed in a 62-year-old woman, its signs regressing almost completely within six weeks during treatment with thyroxine and triiodothyronine. The cause of cerebellar ataxia in association with hypothyroidism remains unknown. No typical morphological changes in the cerebellum have been described. It is assumed that a thyrogenic, specific metabolic factor is responsible which aggravates already existing non-specific cerebellar changes. The prognosis is very good. On the other hand, cerebellar ataxia resulting from congenital hypothyroidism has typical histological cerebellar changes and prognosis is very poor unless thyroid treatment is started soon after birth.