Frailty in older breast cancer survivors: age, prevalence, and associated factors.
Frailty in older breast cancer survivors: age, prevalence, and associated factors.
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DOI：
10.1188/13.onf.e126-e134
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发表时间：
2013-05-01
影响因子：
1.9
通讯作者：
Nail LM
中科院分区：
文献类型：
--
作者：
Bennett JA;Winters-Stone KM;Dobek J;Nail LM
描述乳腺癌幸存者的虚弱和相关因素横断面描述性护理学院216名年龄在53-87岁的乳腺癌幸存者（BCS）目前没有参加运动性能测试、临床测量和自我报告问卷为本研究分析提供了基线数据虚弱被定义为满足虚弱表型5个标准中的3个：萎缩、疲惫、低活动、缓慢和虚弱。将这些数据与心血管健康研究（CHS）和女性健康与衰老研究（WHAS）中发表的女性数据进行比较。70-79岁的BCS中有18%虚弱，而70-79岁的CHS和WHAS女性中有11%虚弱。与CHS妇女相比，BCS中虚弱在年轻时更常见，并且在所有年龄组中，更多的BCS虚弱，直到大约80岁，两组中虚弱的患病率相似。50%的BCS被归类为虚弱前期，因为他们符合5项虚弱标准中的1-2项。较高的身体质量指数增加了虚弱的几率，较高的身体活动降低了虚弱的几率（分别为OR= 1.12, p= 0.003和OR= 0.99, p= 0.000）。衰弱和易感可能在BCS中很常见，并且可能比无癌症史的成年人更早发生。
Describe frailty and associated factors in breast cancer survivors Cross-sectional descriptive School of nursing 216 breast cancer survivors (BCS) aged 53–87 not currently participating in exercise Performance tests, clinical measures, and self-reported questionnaires provided baseline data analyzed for this study Frailty was defined as meeting 3 of the 5 criteria of the Frailty Phenotype: shrinking, exhaustion, low activity, slowness, and weakness. Data were compared to published data from women in the Cardiovascular Health Study (CHS) and Women’s Health and Aging Study (WHAS). 18% of BCS aged 70–79 were frail, compared to 11% of CHS and WHAS women aged 70–79. Frailty was more common at a younger age in BCS and more BCS were frail in all age groups compared to CHS women until approximately age 80 when prevalence of frailty was similar in the two groups. 50% of BCS were classified as prefrail because they met 1–2 of the 5 frailty criteria. Higher body mass index increased the odds of frailty and higher physical activity decreased the odds of frailty (OR= 1.12, p=.003 and OR=.99, p=.000 respectively). Frailty and prefrailty may be common in BCS and may occur at an earlier age than in adults without a history of cancer.