Relationship of Intestinal Eosinophilia and the Acid-fast Bacilli in Johne ’ s Disease
Relationship of Intestinal Eosinophilia and the Acid-fast Bacilli in Johne ’ s Disease
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约内病肠道嗜酸性粒细胞增多与抗酸杆菌的关系
DOI：
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发表时间：
2015
期刊：
影响因子：
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通讯作者：
J. Williams
中科院分区：
文献类型：
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作者：
G. Monif;J. Williams
尸检记录的12头奶牛的肠道和淋巴结切片，晚期疾病分析了由鸟分枝杆菌副结核亚种（MAP）引起的Johne病，以评估固有层内嗜酸性粒细胞的存在与抗酸杆菌的可证实性之间的可能关系。确定了与肠载玻片和相应淋巴结内存在的可证实的抗酸杆菌的量的负相关性。嗜酸性粒细胞的作用，最终破坏分枝杆菌进行了讨论。
Intestinal and lymph node slides from 12 cows that had necropsy documented, advanced disease (Johne’s disease) due to Mycobacterium avium subspecies paratuberculosis (MAP) were analyzed to assess a possible relationship between the presence of eosinophils within the lamina propria and the demonstrability of acid-fast bacilli In three instances where significant eosinophilia was identified, an inverse correlation with the amount of demonstrable acid-fast bacilli present within intestinal slides and corresponding lymph node was identified. The role of eosinophils in the ultimate destruction of mycobacteria is discussed.