Restless legs syndrome and hypertension in Chinese pregnant women
Restless legs syndrome and hypertension in Chinese pregnant women
复制标题
DOI：
10.1007/s10072-015-2094-4
复制
发表时间：
2015-06-01
影响因子：
3.3
通讯作者：
Xue, Rui
中科院分区：
文献类型：
--
作者：
Ma, Shengli;Shang, Xiaoping;Xue, Rui
高血压是妊娠的常见并发症，研究表明，孕妇更容易患上不宁腿综合征(RLS)。患有高血压和RLS的孕妇通常会因为神经系统的激活而睡眠模式被打乱。本研究旨在阐明妊娠期高血压与RLS的关系及其对睡眠的影响。我们招募了3781名孕妇，她们在2011年5月至2014年5月期间在我们医院住院分娩。用于收集数据的面对面问卷包括国际RLS研究小组诊断标准、匹兹堡睡眠质量指数(PSQI)、Epworth嗜睡量表(ESS)和高血压诊断。根据高血压的发生时间，将其分为两种不同的类型：妊娠高血压综合征和妊娠高血压综合征。在3781名患者中，453名符合RLS诊断标准，486名符合高血压诊断标准。在RLS患者中，妊娠期预防性补铁的频率较低。在RLS患者中，妊娠高血压综合征的发生率高于妊娠高血压综合征；RLS孕妇的PSQI和ESS得分高于妊娠对照组。在我们的研究中，RLS在孕妇中很常见，特别是在那些没有预防性补铁的妇女中。RLS患者描述了更严重的睡眠中断和日间过度嗜睡(EDS)。此外，妊娠高血压综合征在RLS患者中更为常见。
Hypertension is a common complication of pregnancy, and studies show that pregnant women are more likely to suffer from restless legs syndrome (RLS). Pregnant women with hypertension and RLS often experience disrupted sleep patterns because of activation of the nervous system. The present study aimed to clarify the relationship between hypertension and RLS in pregnant women, and their impact on sleep. We enrolled 3,781 pregnant women who were admitted at our hospital for delivery between May 2011 and May 2014. The face-to-face questionnaire used to gather data included the International RLS Study Group criteria for diagnosis, Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), and hypertension diagnosis. Depending on the time of occurrence of hypertension, it was divided into two different types: pregnancy-induced hypertension and chronic hypertension in pregnancy. Out of 3,781 patients, 453 fulfilled the diagnostic criteria for RLS and 486 met the diagnostic criteria for hypertension. Among patients with RLS, prophylactic iron supplementation was less frequently taken during pregnancy. Pregnancy-induced hypertension, rather than chronic hypertension in pregnancy, was found to be more frequent in patients with RLS; pregnant women with RLS had higher PSQI and ESS scores than pregnant controls. In our study, RLS was frequent in pregnant women, especially in those without prophylactic iron supplementation. Patients with RLS described more serious sleep disruption and excessive daytime sleepiness (EDS). In addition, pregnancy-induced hypertension was more common in patients with RLS.