Construction of freezing of gait questionnaire for patients with Parkinsonism
Construction of freezing of gait questionnaire for patients with Parkinsonism
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DOI：
10.1016/s1353-8020(99)00062-0
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发表时间：
2000-07-01
影响因子：
4.1
通讯作者：
Korczyn, AD
中科院分区：
文献类型：
--
作者：
Giladi, N;Shabtai, H;Korczyn, AD
背景：步态冻结（FOG）是一种常见的，知之甚少的帕金森症状，干扰日常功能和生活质量。由于这种症状的发作性，以及心理和环境因素对其的影响，FOG的评估是复杂的。目的：设计一份可自我报告的、可靠的FOG问卷。方法：对40例帕金森病（PD）患者（男性26例）进行步态、跌倒等16项问卷调查和统一帕金森病评定量表（UPDRS），这些患者的平均年龄为72.3 +/- 9.3岁，平均Hoehn和Yahr （H&Y）分期为“Off”（2.85 +/- 0.84）。对结果进行了Varimax旋转主成分分析。对一个简短的FOG问卷进行了项目分析和信度计算。结果：基于这些分析，构建了一份简短的（6项）FOG问卷，发现该问卷对FOG的评估具有高可靠性（Cronbach alpha = 0.94），与日常生活活动（ADL）和UPDRS的运动部分具有中等相关性（分别为0.43和0.40）。在UPDRS的ADL部分，也发现了与FOG项目的中度相关性（alpha = 0.66为“关闭”状态，0.77为“打开”状态）。结论：所构建的FOG问卷在评估PD患者与跌倒无关的步态冻结方面是高度可靠的。(C) 2000 Elsevier Science Ltd.版权所有。
Background: Freezing of gait (FOG) is a common, poorly understood, parkinsonian symptom interfering with daily functioning and quality of life. Assessment of FOG is complex because of the episodic nature of this symptom, and the influence of mental and environmental factors on it.Objective: To design a self-reportable reliable questionnaire for FOG.Method: A questionnaire consisting of 16 items regarding gait and falls was administered together with the Unified Parkinson's Disease Rating Scale (UPDRS) to 40 Parkinson's disease (PD) patients (26 males) with a mean age of 72.3 +/- 9.3 years and mean Hoehn and Yahr (H&Y) stage at "Off" of 2.85 +/- 0.84. A principal component analysis with Varimax rotation was conducted on the results. Item analyses were performed and reliability computed for an abbreviated FOG questionnaire.Results: Based on these analyses, a short (six item) FOG questionnaire was constructed, which was found to be highly reliable (Cronbach alpha = 0.94) for assessment of FOG and with moderate correlation with the activity of daily living (ADL) and motor parts of the UPDRS (0.43 and 0.40, respectively). Moderate correlation was also found with the FOG item at the ADL part of the UPDRS (alpha = 0.66 for the "Off" and 0.77 for the "On" state).Conclusion: The FOG questionnaire that was constructed is highly reliable in assessing freezing of gait, unrelated to falls, in patients with PD. (C) 2000 Elsevier Science Ltd. All rights reserved.