Ome's, ic's, and ip's: from the bench to the bedside and back again.
Ome's, ic's, and ip's: from the bench to the bedside and back again.
复制标题
Ome、ic 和 ip：从板凳到床边，然后再回来。
DOI：
10.1016/j.jaac.2013.12.018
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发表时间：
2014
影响因子：
13.3
通讯作者：
Drury,StacyS
中科院分区：
文献类型：
--
作者：
Drury,StacyS
The progress of science often seems to lead in one direction: forward (note how data “advance” a field). And yet, new hypotheses sometimes require a more circuitous path, one that connects past theories, often never proved inaccurate, with “new” data. Never before has the prevalence of mental illness, the fragmented mental health care system, and the lifelong negative impact of early life adversity been so evident. It is amidst this increased attention to mental health that the field of neurogenetics is rapidly evolving through directives such as President Obama’s Brain Initiative (http://www. whitehouse. gov/share/brain-initiative) and the National Institute of Mental Health’s (NIMH) Research Domain Criteria (RDoC)(http://www. nimh. nih. gov/research-priorities/rdoc/index. shtml). Against this backdrop of scientific advancement, it is perhaps the less traveled road, one that brings science back to the foundations of our field instead of away, that is the path to choose.The thoughtful integration of neuroscience and genetics with child developmental theory will position psychiatrists to most effectively respond to NIMH Director Thomas Insel’s statement that “We are not doing well enough for our patients.” Amidst the recent decreases in deaths from cardiovascular disease, cancer, and the re-classification of human immunodeficiency virus as a chronic disease, suicide rates remain static. Psychiatric treatment modalities also remain static, and, for the most part, we remain unable to “cure” mental illness, as Insel reminded us at the Lawrence A. Stone, MD Plenary of the American Academy of Child and Adolescent Psychiatry’s 60th Annual Meeting in Orlando, FL, on October 25, 2013. The specialized developmental knowledge, unique trans-disciplinary skills, and the regular interaction with the diverse professions involved in the care of children who define the practice of child psychiatry are precisely the reasons why our field must orchestrate this integration.
