CT AND MR IMAGING IN STAGING NON-SMALL-CELL BRONCHOGENIC-CARCINOMA - REPORT OF THE RADIOLOGIC-DIAGNOSTIC-ONCOLOGY-GROUP

CT AND MR IMAGING IN STAGING NON-SMALL-CELL BRONCHOGENIC-CARCINOMA - REPORT OF THE RADIOLOGIC-DIAGNOSTIC-ONCOLOGY-GROUP
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DOI:
10.1148/radiology.178.3.1847239
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发表时间:
1991-03-01
期刊:
影响因子:
19.7
通讯作者:
MCNEIL, BJ
MCNEIL, BJ
中科院分区:
医学1区
文献类型:
--
作者:
WEBB, WR;GATSONIS, C;MCNEIL, BJ

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在对170例非小细胞支气管肺癌患者的前瞻性合作研究中,比较了磁共振(MR)成像和计算机断层扫描(CT)在确定肿瘤分类和评估纵隔淋巴结转移方面的准确性。 CT鉴别T3-T4期肿瘤与T0-T2期肿瘤的敏感性为63%,特异性为84%。 MR成像的这些值没有显著差异(56%和80%)。 受试者工作特征(ROC)分析显示,CT和MR诊断支气管受累或胸壁侵犯的准确性无差异,但MRI诊断纵隔侵犯的准确性明显高于CT(P = 0.047)。 对155例患者(642个淋巴结站)进行了淋巴结采样。 在21%的患者中,14%的站点发现了癌性淋巴结。 CT和MR诊断纵隔淋巴结转移(N2或N3)的准确性无显著差异,敏感性分别为52%和48%,特异性分别为69%和64%。 ROC分析也显示CT和MR成像之间没有差异。
The accuracies of magnetic resonance (MR) imaging and computed tomography (CT) in determining tumor classification and assessing mediastinal node metastases were compared in a prospective cooperative study of 170 patients with non-small cell bronchogenic carcinoma. The sensitivity of CT in distinguishing T3-T4 tumors from T0-T2 tumors was 63%; specificity was 84%. These values for MR imaging were not significantly different (56% and 80%). With receiver operating characteristic (ROC) analysis, no difference existed between the accuracies of CT and MR imaging in diagnosis of bronchial involvement or chest wall invasion, but MR imaging was significantly more accurate than CT (P = .047) in diagnosis of mediastinal invasion. Lymph node sampling was performed in 155 patients (642 node stations). Cancerous nodes were found in 14% of stations in 21% of patients. There was no significant difference between the accuracies of CT and MR imaging in detecting mediastinal node metastases (N2 or N3); the sensitivities were 52% and 48%, respectively, and specificities were 69% and 64%. ROC analysis also showed no difference between CT and MR imaging.