INTESTINAL LOOP LENGTHENING - A TECHNIQUE FOR INCREASING SMALL INTESTINAL LENGTH
INTESTINAL LOOP LENGTHENING - A TECHNIQUE FOR INCREASING SMALL INTESTINAL LENGTH
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DOI：
10.1016/s0022-3468(80)80005-4
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发表时间：
1980-01-01
影响因子：
2.4
通讯作者：
BIANCHI, A
中科院分区：
文献类型：
--
作者：
BIANCHI, A
描述了一种可重复的技术，用于使小肠环的长度加倍，同时减小其管腔直径并保留最大量的小肠粘膜用于肠适应。在猪实验中，通过“肠袢延长”程序增加了7个肠袢的长度，7只动物中有5只存活了16-26周。从延长的肠段泄漏导致1只动物死亡。在第二次手术时，或在实验结束时，所有7个延长的环具有良好的血液供应，并且沿其全长沿着。对研究第1阶段的4份标本中的3份进行组织学检查，确认其存活能力。讨论了肠袢延长术在短肠综合征治疗中的潜在应用。
A reproducible technique is described for doubling the length of a loop of small intestine, while simultaneously reducing its luminal diameter and preserving the maximum amount of small bowel mucosa for intestinal adaptation. In pig experiments, 7 loops have been increased in length by the "intestinal loop lengthening" procedure, with survival of 5 of the 7 animals for a period of 16-26 wk. Leakage from the lengthened intestinal segment led to the death of 1 animal. At a 2nd operation, or at termination of the experiment, all 7 lengthened loops had a good blood supply and were patent along their full length. Histologic examination of 3 of the 4 specimens from the 1st phase of the study confirmed their viability. The potential application of intestinal loop lengthening in the management of the short gut syndrome is discussed.