Genome Sequence of Acinetobacter baumannii MDR-TJ
Genome Sequence of Acinetobacter baumannii MDR-TJ
复制标题
鲍曼不动杆菌 MDR-TJ 基因组序列
DOI：
10.1128/jb.00226-11
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发表时间：
2011-05-01
影响因子：
3.2
通讯作者：
Huang, He
中科院分区：
文献类型：
--
作者：
Gao, Feng;Wang, Yue;Huang, He
鲍曼不动杆菌是一种致病菌，鉴定为需氧革兰氏阴性菌，对大多数抗生素耐药。分离自天津医科大学第二医院中国的耐多药菌株对青霉素、头孢菌素类、氨基糖苷类、喹诺酮类、亚胺培南等耐药。鲍曼不动杆菌MDR-TJ株的基因组序列测定采用454焦糖测序和双端测序相结合的方法，使用罗氏基因组测序仪FLX系统生成支架组装。
Acinetobacter baumannii is a pathogenic species of bacteria, identified as an aerobic Gram-negative bacterium, that is resistant to most antibiotics. In this study, the MDR-TJ strain was isolated at the Second Hospital of Tianjin Medical University, China, and was found to be resistant to penicillin, cephalosporins, aminoglycosides, quinolones, and also imipenem. The genome sequence of Acinetobacter baumannii strain MDR-TJ was determined by using a combination of 454 pyrosequencing and paired-end sequencing performed with the Roche Genome Sequencer FLX system to generate a scaffolded assembly.