STUDY OF 126266 CONSECUTIVE BIRTHS FOR MAJOR CONGENITAL DEFECTS
STUDY OF 126266 CONSECUTIVE BIRTHS FOR MAJOR CONGENITAL DEFECTS
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DOI：
10.1007/bf02722422
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发表时间：
1989-01-01
影响因子：
4.3
通讯作者：
GHOSH P K
中科院分区：
文献类型：
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作者：
CHOUDHURY A R;MUKHERJEE M;GHOSH P K
对西孟加拉5家医院的115，851例连续分娩进行了回顾性研究，并对1家医院的10，415例连续分娩进行了前瞻性研究。先天性缺陷的总体发生率为每1 000名活产婴儿4.42例。新生儿先天畸形和畸形足在雨季发病率最高，腭裂伴兔唇和不伴兔唇在冬季发病率最高。这些异常的发生率随着出生顺序的增加而降低。随着母亲年龄的增加，畸形儿的发生率下降，21-25岁年龄组畸形儿的数量最多。性别比例和宗教信仰与这些畸形的发生率无相关性。在对城市和农村人口进行比较时，没有观察到统计上的显著差异。
Retrospective study was carried out in 115,851 consecutive births in five hospitals, and prospective study of 10,415 consecutive births in one hospital of West Bengal. The overall frequency of congenital defects was 4.42/1000 live births. Incidence of NTD and talipes was predominant in rainy season, whereas cleft palate with/without hare lip had highest frequency during winter. Incidence of these anomalies decreased with increasing birth order. The frequency was noted to decline with increasing maternal age, 21-25 years age group had maximum number of malformed babies. Sex ratio and religion, however, did not have any correlation with the incidence of these malformations. When comparison was done between urban and rural population no statistically significant variation was observed.