Pathology: Commonly Monitored Glioblastoma Markers: EFGR, EGFRvIII, PTEN, and MGMT
Pathology: Commonly Monitored Glioblastoma Markers: EFGR, EGFRvIII, PTEN, and MGMT
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DOI:
10.1016/j.nec.2012.01.011
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发表时间:
2012-04-01
影响因子:
2.6
通讯作者:
Li, Gordon
中科院分区:
文献类型:
--
作者:
Camara-Quintana, Joaquin Q.;Nitta, Ryan T.;Li, Gordon
The purpose of this article is to update the neurosurgical field on current molecular markers important to glioblastoma biology, treatment, and prognosis. The highlighted biologic markers in this article include epidermal growth factor receptor (EGFR), EGFR variant Ill (EGFRvIII), phosphatase and tensin homolog deleted on chromosome 10 (PTEN), and O6-methylguanine-DNA methyltransferase (MGMT).