Prevalence and risk factors of adenomyosis at hysterectomy
Prevalence and risk factors of adenomyosis at hysterectomy
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DOI：
10.1093/humrep/16.11.2418
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发表时间：
2001-11-01
影响因子：
6.1
通讯作者：
Hertz, JB
中科院分区：
文献类型：
--
作者：
Bergholt, T;Eriksen, L;Hertz, JB
背景：本研究旨在评估子宫腺肌病的患病率以及可能的相关危险因素。
方法：检索了1990年至1991年两年期间549例连续接受子宫切除术的女性的病历，并对组织病理学材料进行了重新检查。
结果：根据不同的诊断标准，本研究中子宫腺肌病的患病率在10.0% - 18.2%之间。子宫切除时子宫内膜增生的存在是与子宫腺肌病显著相关的唯一变量（优势比 = 3.0；95%置信区间：1.2 - 8.3）。在子宫腺肌病与既往剖宫产、子宫内膜刮宫或子宫排空之间未发现有统计学意义的关联。此外，我们未发现子宫腺肌病与疼痛相关症状、子宫切除的指征、年龄、产次或子宫肌层样本数量之间有任何显著关联。
结论：我们的研究强调了子宫腺肌病精确诊断标准的必要性，并且进一步表明子宫内膜增生和子宫腺肌病可能有共同的病因。
BACKGROUND: The present study was performed to evaluate the prevalence and possible associated risk factors for adenomyosis. METHODS: Medical records were retrieved and histo-pathological material re-examined for 549 consecutive women undergoing hysterectomy in a two-year period from 1990-1991. RESULTS: The prevalence of adenomyosis in the study varied from 10.0-18.2%, depending on different diagnostic criteria. The presence of endometrial hyperplasia at the time of hysterectomy was the only variable significantly associated with adenomyosis (OR = 3.0; 95% CI: 1.2-8.3). No statistically significant association was found between adenomyosis and previous caesarean section, endometrial curettage or evacuation of the uterus. Furthermore, we did not see any significant association between adenomyosis and pain-related symptoms, indication for hysterectomy, age, parity or number of myometrial samples. CONCLUSIONS: Our study stresses the need for precise diagnostic criteria for adenomyosis, and furthermore indicates that endometrial hyperplasia and adenomyosis may have a common aetiology.