Theory of lipid monolayer and bilayer chain-melting phase transitions.
Theory of lipid monolayer and bilayer chain-melting phase transitions.
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脂质单层和双层链熔化相变理论。
DOI：
10.1039/dc9868100151
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
Nagle,JF
中科院分区：
文献类型：
--
作者：
Nagle,JF
最近对空气-水界面脂质单层的实验表明，每个分子小区域的相变是一级链熔融转变，类似于双层中观察到的熔融转变。这个结果与旧的统计力学理论的结果是一致的。在本文中，对适用于单层和双层的旧理论之一进行了新的计算。该理论采用了一种过于简化但严格可解的统计力学模型来排除烃链之间的体积相互作用。在新的计算中，有效的范德华内聚相互作用被修改以补偿模型维度的降低。双层相变的大小现在与实验更加一致。
Recent experiments on lipid monolayers at the air–water interface show that the phase transition at small areas per molecule is a first-order chain-melting transition similar to the melting transition observed in bilayers. This result is in agreement with the results of older statistical-mechanical theories. In this paper new calculations are performed for one of the older theories which applies to both monolayers and bilayers. This theory employs an oversimplified, but rigorously solvable, statistical-mechanical model for the excluded volume interactions between hydrocarbon chains. In the new calculations the effective van der Waals cohesive interaction is modified to compensate for the reduced dimensionality of the model. The size of the bilayer phase transition is now in much better agreement with experiment.