Effect of naltrexone on stress-induced bioactive prolactin release in aging male rats.
Effect of naltrexone on stress-induced bioactive prolactin release in aging male rats.
复制标题
纳曲酮对衰老雄性大鼠应激诱导的生物活性催乳素释放的影响。
DOI：
10.1016/0197-4580(91)90053-m
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发表时间：
1991
影响因子：
4.2
通讯作者：
Sylvester,PW
中科院分区：
文献类型：
--
作者：
Briski,KP;Sylvester,PW
Effects of the opiate receptor antagonist naltrexone (NALT, 10 mg/kg) on basal and novel environment stress-induced prolactin (PRL) release were examined in young (3–5 month) and old (22–24 month) male Copenhagen-Fischer 344 rats. Radioimmunoassay and Nb2lymphoma bioassay were used to determine plasma immunoreactive (ir-) and bioactive (bio-) PRL levels, respectively. Although basal plasma irPRL levels were greater, bioPRL levels were significantly lower in old as compared to young rats. NALT induced significant decreases in basal plasma ir- and bioPRL concentrations in young rats, but had little or no effect on irPRL or bioPRL levels in old rats. Stress-induced elevations in irPRL levels were similar, but increases in bioPRL levels were attenuated in vehicle-treated old as compared to young rats. NALT pretreatment blocked stress-induced ir- and bioPRL release in both age groups. These results indicate that the role of endogenous opioid peptides (EOP) in regulating basal PRL secretion appears to be diminished, whereas EOP continue to be involved in stress-induced PRL release in the aging animal.
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影响因子：
3.6
作者：
KETCHUM, LD;MARTIN, NL;KAPPEL, DA
通讯作者：
KAPPEL, DA
DOI：
10.1016/s0039-6109(16)37543-0
发表时间：
1965
期刊：
The Surgical clinics of North America
影响因子：
--
作者：
E. Peacock
通讯作者：
E. Peacock
组织培养中的内在肌腱细胞增殖。
影响因子：
1.9
作者：
H. Becker;M. Graham;I. Cohen;R. Diegelmann
通讯作者：
R. Diegelmann
DOI：
10.1016/s0266-7681(84)80005-4
发表时间：
1984-01-01
期刊：
JOURNAL OF HAND SURGERY-BRITISH AND EUROPEAN VOLUME
影响因子：
--
作者：
MANSKE, PR;LESKER, PA
通讯作者：
LESKER, PA
使用氢冲洗技术到达屈肌腱的营养途径。
DOI：
10.1016/s0363-5023(78)80115-4
发表时间：
1978
期刊：
The Journal of hand surgery
影响因子：
--
作者：
P. Manske;L. Whiteside;P. Lesker
通讯作者：
P. Lesker