PERSISTENT PARA-INFLUENZA VIRUS SHEDDING DURING ISOLATION AT THE SOUTH-POLE

PERSISTENT PARA-INFLUENZA VIRUS SHEDDING DURING ISOLATION AT THE SOUTH-POLE
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DOI:
10.1038/289187a0
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发表时间:
1981-01-01
期刊:
影响因子:
64.8
通讯作者:
MILES, JAR
MILES, JAR
中科院分区:
综合性期刊1区
文献类型:
--
作者:
MUCHMORE, HG;PARKINSON, AJ;MILES, JAR

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健康年轻人在 8 1/2 个月内持续出现副流感病毒脱落。 1978 年阿蒙森-斯科特南极站的冬季隔离期。在完全社会隔离 10 周和 29 周后观察到两次呼吸道疾病发作。定期收集的咽拭子以及每次呼吸道疾病爆发期间收集的咽拭子都直接接种到细胞培养物中。整个冬季,从有症状和无症状受试者中回收了 1 型和 3 型副流感病毒。通过这些努力没有获得其他病毒。在病毒性上呼吸道疾病的公认潜伏期很久之后,并且当不可能将新病毒引入该群体时,副流感病毒在这些受试者中仍然存在,这表明副流感病毒在人类中持续存在。
Persistent parainfluenza virus shedding in healthy young adults occurred through the 8 1/2 mo. winter isolation period at Amundsen-Scott South Pole Station during 1978. Two episodes of respiratory illness were observed after 10 and 29 wk of complete social isolation. Throat swabs collected routinely and during each outbreak of respiratory illness were directly inoculated into cell cultures. Parainfluenza virus types 1 and 3 were recovered from symptomatic and asymptomatic subjects throughout the winter. No other viruses were obtained by these efforts. The presence of parainfluenza virus in these subjects long after the accepted incubation period for viral upper respiratory illness, and when the introduction of new virus to this community was impossible, suggests its persistence in man.