Endobiliary Radiofrequency Ablation Using a Short-Type Balloon Enteroscope in Patients with Surgically Altered Anatomy

Endobiliary Radiofrequency Ablation Using a Short-Type Balloon Enteroscope in Patients with Surgically Altered Anatomy
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使用短型球囊肠镜对解剖结构发生手术改变的患者进行胆内射频消融

DOI:
10.1007/s10620-021-07224-7
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发表时间:
2022
影响因子:
3.1
通讯作者:
Yoneda Masashi
Yoneda Masashi
中科院分区:
医学3区
文献类型:
--
作者:
Inoue Tadahisa;Ibusuki Mayu;Kitano Rena;Sakamoto Kazumasa;Kimoto Satoshi;Kobayashi Yuji;Ohashi Tomohiko;Sumida Yoshio;Nakade Yukiomi;Ito Kiyoaki;Yoneda Masashi

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背景经内窥镜射频消融(RFA)有望延长恶性胆道梗阻(MBO)的支架通畅率。然而,在外科解剖改变(SAA)患者中联合使用球囊肠镜(BE)的可行性尚不清楚。目的本研究旨在探讨BE引导下射频消融联合金属支架置入治疗外科解剖改变(SAA)患者的可行性。研究结果包括技术和临床上的成功、再发胆道梗阻(RBO)和其他不良事件,除了RFA和BE金属支架置入术相关的RBO外。早期不良事件发生率为8.1%(3/37),晚期不良事件发生率为8.1%(3/37)。RBO发生率为32.4%(12/37),中位RBO时间为296天。RBO的原因是内生性生长8例,过度生长3例,不明原因1例。使用BE方法,所有的RBO再介入治疗都是成功的;除了一个,所有的植入都使用了额外的RFA,而不需要额外的支架放置。再干预相关不良事件发生率为9.1%(1/11)。再次介入术后中位RBO时间为166天。结论BE引导下胆道内射频消融术联合金属支架置入术技术安全可行,远期疗效良好。这种方法可能是治疗SAA患者MBO的一个有用的选择。
BackgroundEndoscopic radiofrequency ablation (RFA) is expected to prolong stent patency for malignant biliary obstruction (MBO). However, its feasibility when used in conjunction with a balloon enteroscope (BE) in patients with surgically altered anatomy (SAA) remains unknown.AimsThis study aimed to investigate the feasibility of RFA combined with metal stent insertion under BE guidance for MBO in patients with SAA.MethodsThirty-seven patients who underwent treatment between October 2016 and January 2021 and met the eligibility criteria were investigated retrospectively. Study outcomes included technical and clinical success, recurrent biliary obstruction (RBO), and other adverse events besides RBO associated with RFA with metal stent placement using BE.ResultsTechnical and clinical success rates were 100% (37/37) each. The rates of early and late adverse events were 8.1% (3/37) and 8.1% (3/37), respectively. RBO occurred in 32.4% (12/37) of the patients, and the median time to RBO was 296 days. The cause of RBO was ingrowth in eight patients, overgrowth in three patients, and indeterminate in one patient. All reinterventions for RBO were successful using the BE approach; all ingrowths, except one, were recanalized using additional RFA without additional stent placement. The frequency of reintervention-related adverse events was 9.1% (1/11). The median time to RBO after reintervention was 166 days.ConclusionsThis study demonstrated the technical safety and feasibility as well as good long-term outcomes of endobiliary RFA combined with metal stent placement under BE guidance. This approach may be a useful option for treating MBO in patients with SAA.
DOI: 10.1111/den.13854
发表时间: 2020-11-11
影响因子: 5.3
作者:
Inoue, Tadahisa;Naitoh, Itaru;Yoneda, Masashi
通讯作者: Yoneda, Masashi
使用短型单球囊内窥镜射频消融联合多个胆道金属支架植入术治疗手术改变解剖结构的患者
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发表时间: 2018
影响因子: 5.3
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