Perceived efficacy of HIV treatment-as-prevention among university students in Johannesburg, South Africa.
Perceived efficacy of HIV treatment-as-prevention among university students in Johannesburg, South Africa.
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DOI：
10.1136/sextrans-2021-055031
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发表时间：
2021-12
影响因子：
3.6
通讯作者：
Evans D
中科院分区：
文献类型：
--
作者：
Bor J;Musakwa N;Onoya D;Evans D
抗逆转录病毒疗法（ART）几乎消除了艾滋病毒的传播。然而，在撒哈拉以南非洲，关于以治疗为预防的信息传播缓慢。我们评估了南非大学生的TasP知识。我们对南非约翰内斯堡一所大型公立大学的一年级学生进行了一项横断面调查，他们都是最近完成了中学艾滋病毒课程的学生。受访者被要求考虑艾滋病毒传播的可能性，在血清不一致的夫妇有无避孕套的性行为与病毒抑制ART。信念引起使用0-20视觉尺度。我们将信念与科学文献的估计值进行比较，并评估与人口统计学、HIV检测史和HIV知识和风险感知的定性测量的相关性。该分析包括365名18-25岁的大学生（48%为女性，56%来自豪登省）。平均而言，使用病毒抑制性ART的艾滋病毒传播年风险为73%;客观风险<1%。平均而言，受访者认为抑制病毒的ART使年传播风险降低了17%;风险的客观降低率> 96%。我们没有观察到受试者特征和测试历史对TasP功效的感知差异。认为TasP的疗效与（正确）的信念，即艾滋病毒的风险增加性频率。南非的大学生低估了艾滋病毒治疗的预防效益。对TasP的了解不足可能会限制年轻人对艾滋病毒检测和治疗的需求。
Antiretroviral therapy (ART) nearly eliminates HIV transmission. Yet information on treatment as prevention (TasP) has been slow to diffuse in sub-Saharan Africa. We assessed TasP knowledge among university students in South Africa. We conducted a cross-sectional survey of first-year university students at a large public university in Johannesburg, South Africa, all of whom would have recently completed secondary school HIV curricula. Respondents were asked to consider the likelihood of HIV transmission in a serodiscordant couple having condomless sex with and without virally suppressive ART. Beliefs were elicited using a 0–20 visual scale. Perceived TasP efficacy was computed as the relative reduction in risk associated with virally suppressive ART. We compared beliefs with estimates from the scientific literature and assessed associations with demographics, HIV testing history and qualitative measures of HIV knowledge and risk perception. The analysis included 365 university students ages 18-25 years (48% female, 56% from Gauteng Province). On average, perceived annual risk of HIV transmission with virally suppressive ART was 73%; the objective risk is <1%. On average, respondents perceived that virally suppressive ART reduced annual transmission risk by 17%; the objective reduction in risk is >96%. We observed no differences in perceived TasP efficacy by participant characteristics and testing history. Perceived TasP efficacy was correlated with the (correct) belief that HIV risk increases with sexual frequency. University students in South Africa underestimated the prevention benefits of HIV treatment. Low knowledge of TasP could limit demand for HIV testing and treatment among young adults.
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DOI：
10.1097/qad.0000000000000307
发表时间：
2014-06-19
期刊：
AIDS (London, England)
影响因子：
--
作者：
Lasry A;Sansom SL;Wolitski RJ;Green TA;Borkowf CB;Patel P;Mermin J
通讯作者：
Mermin J
影响因子：
56.3
作者：
Boily, Marie-Claude;Baggaley, Rebecca F.;Wang, Lei;Masse, Benoit;White, Richard G.;Hayes, Richard J.;Alary, Michel
通讯作者：
Alary, Michel
影响因子：
3.7
作者：
Bavinton, Benjamin R.;Holt, Martin;Prestage, Garrett P.
通讯作者：
Prestage, Garrett P.
DOI：
10.1097/qai.0000000000001557
发表时间：
2018-01-01
期刊：
Journal of acquired immune deficiency syndromes (1999)
影响因子：
--
作者：
Card KG;Armstrong HL;Lachowsky NJ;Cui Z;Sereda P;Carter A;Montaner JSG;Hogg RS;Roth EA;Moore DM
通讯作者：
Moore DM
影响因子：
4.4
作者：
Ndyabakira, Alex;Chamie, Gabriel;Thirumurthy, Harsha
通讯作者：
Thirumurthy, Harsha