Asbestosis, pleural plaques and diffuse pleural thickening: three distinct benign responses to asbestos exposure
Asbestosis, pleural plaques and diffuse pleural thickening: three distinct benign responses to asbestos exposure
复制标题
DOI：
10.1183/09031936.98.11051021
复制
发表时间：
1998-05-01
影响因子：
24.3
通讯作者：
Sergent, G
中科院分区：
文献类型：
--
作者：
Gevenois, PA;de Maertelaer, V;Sergent, G
本研究的目的是通过计算机断层扫描（CT）研究石棉肺、弥漫性胸膜增厚和/或胸膜斑块是否有统计学相关性，我们还试图找到区分弥漫性胸膜增厚和局限性胸膜增厚的标准。只有那些X线片既未显示双侧钙化胸膜斑块，也未显示肺部小阴影高于1/根据1980年国际劳工局（ILO）的分类，考虑了1个等级。CT检查发现胸膜下曲线、间隔和小叶内线、实质带、蜂窝样改变、圆形肺不张、胸膜斑块和弥漫性胸膜增厚。弥漫性胸膜增厚、实质条索和圆形肺不张分别在62、69和75%的异常病例中为单侧。间隔线、小叶内线和蜂窝样改变均为双侧。CT征象可分为三种类型：1）小叶内、小叶间隔线及蜂窝样改变对应肺纤维化，2）胸膜斑对应壁层胸膜纤维化，3）胸膜纤维化对应胸膜纤维化。3）弥漫性胸膜增厚、圆形肺不张和实质条索，对应于内脏胸膜纤维化。在这些X线片正常或接近正常的工人中，区分了三组具有不同反应的受试者，鱼尾纹和圆形肺不张有助于鉴别斑块和弥漫性增厚。
The aim of this study was to investigate by computed tomography (CT) whether asbestosis, diffuse pleural thickening and/or pleural plaques are statistically associated, We also tried to find criteria to differentiate between diffuse and circumscribed pleural thickening,From 231 exposed workers, only those subjects whose radiograph showed neither bilateral calcified pleural plaques nor small pulmonary opacities higher than 1/1 grade according to the 1980 International Labour Office (ILO) Classification were considered. Scans were assessed for the presence of subpleural curvilinear lines, septal and intralobular lines, parenchymal bands, honeycombing, rounded atelectasis, pleural plaques and diffuse pleural thickening.CT scans revealed pleural and/or lung abnormalities in 99 workers, Pleural plaques were unilateral in one-third of cases with plaques. Diffuse pleural thickening, parenchymal bands and rounded atelectasis were unilateral in, respectively, 62 and 69 and 75% of cases with the abnormality. Septal and intralobular lines, and honeycombing were always bilateral. CT signs could be grouped into three patterns: 1) septal and intralobular lines, and honeycombing corresponding to pulmonary fibrosis; 2) pleural plaques col responding to parietal pleural fibrosis; and 3) diffuse pleural thickening, rounded atelectasis and parenchymal bands corresponding to visceral pleural fibrosis,In these workers with a normal or near-normal radiograph, three groups of subjects with different responses were distinguished, Crow's feet and rounded atelectasis help to differentiate plaques from diffuse thickening.