Cytotoxicities of a 4-META/MMA-TBBO resin against human pulp fibroblasts.
Cytotoxicities of a 4-META/MMA-TBBO resin against human pulp fibroblasts.
复制标题
4-META/MMA-TBBO 树脂对人牙髓成纤维细胞的细胞毒性。
作者：
S. Fujisawa;T. Atsumi
本研究旨在研究甲基丙烯酸甲酯(MMA)和4-甲基丙烯酰氧乙氧基酮基邻苯二甲酸酐(4-Meta)/MMA在引发剂三丁基硼烷部分氧化物(TBBO)和单独使用时对人牙髓成纤维细胞(HPF)的细胞毒作用。用四甲基偶氮唑盐比色法测定细胞存活率。4-META/MMA-TBBO的细胞毒性与MMA-TBBO相当。TBBO具有比4-META/MMA更高的细胞毒性。4-META/MMA-TBBO树脂的细胞毒性诱导可能与TBBO有较好的相关性。
This study was designed to investigate the cytotoxicity of MMA (methyl methacrylate) and 4-META (4-methacryloyloxyethoxycarbonylphthalic anhydride)/MMA with or without TBBO (tri-n-butylborane partially oxide), an initiator and TBBO alone against human pulp fibroblasts (HPF). Cell viabilities were measured by MTT assay. The cytotoxicity of 4-META/MMA-TBBO was comparable with that of MMA-TBBO. TBBO showed higher cytotoxicity than 4-META/MMA. The cytotoxicity induction of a 4-META/MMA-TBBO resin may be preferably associated with TBBO.