Variables Contributing to Acute Mountain Sickness on the Summit of Mt Whitney

Variables Contributing to Acute Mountain Sickness on the Summit of Mt Whitney
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导致惠特尼山山顶急性高山病的变量

DOI:
10.1580/pr43-05.1
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发表时间:
2006
影响因子:
2.4
通讯作者:
T. A. Young
T. A. Young
中科院分区:
医学4区
文献类型:
--
作者:
D. Wagner;J. Fargo;D. Parker;Kevin Tatsugawa;T. A. Young

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抽象目标。15个变量代表的物理特性,以前的海拔暴露,和上升数据的相互作用进行了分析,以确定其对急性高山病(AMS)的贡献。方法。- 359名志愿者在到达惠特尼山(4419米)山顶时获得了照片。用脉搏血氧仪测量心率和动脉血氧饱和度,并通过露易丝湖自我评估评分确定AMS。多元Logistic回归分析用于确定AMS的重要保护因素和危险因素。结果。- 33%的样本符合AMS标准。报告有高原病史的人(调整后的比值比[OR] = 2.00,P <0.01)或在攀登过程中服用止痛药的人(调整后的OR = 2.09,P <0.01)发生AMS的几率更大。AMS的发生率随着年龄的增加而降低(调整后的OR = 0.82,P <0.0001),在过去一个月内攀登3000 m以上的次数增加(调整后的OR = 0.92,P <0.05),以及在攀登过程中使用乙酰唑胺(调整后的OR = 0.33,P <0.05)。结论。的显着的决定因素AMS的惠特尼山山顶的年龄,高原疾病的历史,在过去的一个月内超过3000米的攀登次数,并使用乙酰唑胺和镇痛药在上升。
Abstract Objective.—The interaction of 15 variables representing physical characteristics, previous altitude exposure, and ascent data was analyzed to determine their contribution to acute mountain sickness (AMS). Methods.—Questionnaires were obtained from 359 volunteers upon reaching the summit of Mt Whitney (4419 m). Heart rate and arterial oxygen saturation were measured with a pulse oximeter, and AMS was identified by Lake Louise Self-Assessment scoring. Multiple logistic regression analysis was used to identify significant protective and risk factors for AMS. Results.—Thirty-three percent of the sample met the criteria for AMS. The odds of experiencing AMS were greater for those who reported a previous altitude illness (adjusted odds ratio [OR] = 2.00, P < .01) or who were taking analgesics during the ascent (adjusted OR = 2.09, P < .01). Odds for AMS decreased with increasing age (adjusted OR = 0.82, P < .0001), a greater number of climbs above 3000 m in the past month (adjusted OR = 0.92, P < .05), and use of acetazolamide during the ascent (adjusted OR = 0.33, P < .05). Conclusions.—The significant determinants of AMS on the summit of Mt Whitney were age, a history of altitude illness, number of climbs above 3000 m in the past month, and use of acetazolamide and analgesics during ascent.
DOI: 10.1093/oxfordjournals.aje.a115101
发表时间: 1989-01-01
影响因子: 5
作者:
MICKEY, RM;GREENLAND, S
通讯作者: GREENLAND, S
DOI: 10.1089/152702902753639522
发表时间: 2002-03-01
影响因子: 2.1
作者:
Gertsch, JH;Seto, TB;Onopa, J
通讯作者: Onopa, J