Recent advances in functional nanostructures as cancer photothermal therapy.
Recent advances in functional nanostructures as cancer photothermal therapy.
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DOI：
10.2147/ijn.s161031
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发表时间：
2018
影响因子：
8
通讯作者：
Elzatahry AA
中科院分区：
文献类型：
--
作者：
Hussein EA;Zagho MM;Nasrallah GK;Elzatahry AA
光热疗法作为一种非侵入性、相对安全的治疗技术，在肿瘤治疗领域引起了人们的极大兴趣。近年来，纳米结构技术因其能够吸收近红外辐射以及高效的光热转换而进入癌症治疗的前沿。在这项研究中，讨论了用于癌症治疗的关键纳米结构，包括金纳米颗粒、磁性氧化铁纳米颗粒、有机纳米材料和新型二维纳米制剂如MXenes。此外，我们简要讨论了这些光热纳米材料的纳米结构的特点，同时重点讨论了纳米结构如何作为癌症治疗的潜力。最后，这篇综述为新的癌症治疗方法，特别是体内和体外癌症治疗提供了有前景的见解。
Being a non-invasive and relatively safe technique, photothermal therapy has attracted a lot of interest in the cancer treatment field. Recently, nanostructure technology has entered the forefront of cancer therapy owing to its ability to absorb near-infrared radiation as well as efficient light to heat conversion. In this study, key nanostructures for cancer therapy including gold nanoparticles, magnetite iron oxide nanoparticles, organic nanomaterials, and novel two-dimensional nanoagents such as MXenes are discussed. Furthermore, we briefly discuss the characteristics of the nanostructures of these photothermal nanomaterial agents, while focusing on how nanostructures hold potential as cancer therapies. Finally, this review offers promising insight into new cancer therapy approaches, particularly in vivo and in vitro cancer treatments.