Prefrontal cortex activity during flexible categorization.

Prefrontal cortex activity during flexible categorization.
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DOI:
10.1523/jneurosci.4837-09.2010
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发表时间:
2010-06-23
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
通讯作者:
Miller EK
Miller EK
中科院分区:
其他
文献类型:
--
作者:
Roy JE;Riesenhuber M;Poggio T;Miller EK

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根据行为上下文,项目的分类方式不同。例如,狮子可以是非洲动物或一种猫。我们记录了侧前额叶皮层(PFC)的神经活动,而猴子之间切换分类相同的图像集沿着两个不同的类别计划与正交边界。我们发现,每个类别的计划在很大程度上是由独立的PFC神经元群体和活动反映类别的区别是较弱的,但不是不存在的,当该类别是不相关的。我们建议前额叶皮层独立地代表竞争性类别表征,以减少它们之间的干扰。
Items are categorized differently depending on the behavioral context. For instance, a lion can be an African animal or a type of cat. We recorded lateral prefrontal cortex (PFC) neural activity while monkeys switched between categorizing the same image set along two different category schemes with orthogonal boundaries. We found that each category scheme was largely represented by independent PFC neuronal populations and that activity reflecting a category distinction was weaker, but not absent, when that category was irrelevant. We suggest that the PFC represents competing category representations independently to reduce interference between them.